Virology Live #7: Transcription and RNA processing

When DNA viral genomes enter the cell, mRNAs must be made before DNA replication can occur. This step, called transcription, can only occur on double-stranded templates. The enzyme that carries out transcription, DNA dependent RNA polymerase, may be encoded by the cell or by the viral genome. In this session we discuss regulation of transcription, positive feedback loops and transcriptional cascades and how these coordinate the synthesis of viral DNA and structural proteins. We also consider RNA processing, the addition of a 5'-cap, poly(A) tail, and splicing, the myriad of noncoding RNAs and RNA methylation that can regulate gene expresssion.

——————————— CONNECT ———————————
Twitter: @profvrr

——————————— MORE VIROLOGY ———————————

——————————— OUR OTHER PODCASTS ———————————

– Who Am I? –

I’m Vincent Racaniello, Earth’s Virology Professor.

I’m also a professor of virology at Columbia University in New York. I’ve been doing research on viruses since 1976, and teaching virology in classrooms and online since 1999. On this YouTube channel I share videos of my lectures, podcasts, and more.

New videos are uploaded every Thursday and Sunday mornings.

I do not run ads on our work as it is disruptive to learning. We depend on your support.

———————————————————————
#microbe #viruses #lecture #COVID-19
———————————————————————

[xevUT]

Thoroughly fascinating, especially for those of us without any previous background in (micro-)biology. Took me two viewings but in the end I feel like I have a decent comrehension of the material.

[MrOzzyCam]

Thanks Vincent for another great class!

[rbkuwar]

Great lecture prof. Thank you so much .