Introduction to Embryology - Fertilisation to Gastrulation (Easy to Understand)

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If you find embryology difficult to understand, then this should be the first video you watch. This video covers the basic concepts from ovulation to the formation of the trilaminar germ disc (which will turn into YOU!).

Post any questions you have about the video below, I read all the comments:

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SUMMARY OF VIDEO:

First week of development: Ovulation to Implantation
1. After ovulation the oocyte is transported through the uterine tube.
2. Fertilisation (fusion of a sperm with the oocyte) occurs in the ampulla of the oviduct. For fertilisation to occur, both capacitation and acrosome reaction occur (not explained in video but important to know).
3. Cleavage and blastocyst formation occur.
4. Implantation into the uterine wall.

Second week of development: Bilaminar Germ Disc
1. Trophoblast differentiates into the cytotrophoblast and the syncytiotrophoblast.
2. Epiblast and hypoblast layers develop.
3. Small cavities form the amniotic cavity and yolk sac.
4. Blastocyst completely embedded in the uterus, but it produces a slight protrusion into the lumen of the uterus.
5. Syncytiotrophoblast penetrates deeper and erode the endothelial lining of the maternal capillaries. These capillaries are congested and dilated (sinusoids).
6. Uteroplacental circulation is established.

Third week of development: Trilaminar Germ Disc
1. Gastrulation occurs, beginning with the appearance of the primitive streak.
2. Epiblast cells move inward (invaginate) to form new cell layers, the endoderm and the mesoderm.
3. Cells that do not migrate through the streak but remain in the epiblast form ectoderm.
Note: the epiblast gives rise to all three germ layers, and these layers form all of the tissues and organs.

MORE EMBRYOLOGY:

Embryology of the Heart:

Embryology of the CNS:

Embryology of the Kidney:
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Easy Embryology (written by me) is the BEST textbook to use if you're infuriated with embryology. Get 20% off with code EASY20

minass
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Literally the cutest lecturer "this will become you" / "this will become this" (points to self) thanks for the amazing video! It was very easy to understand with the great explanations and drawings!

hellohelloitsmehi
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In gastrulation, all three germ layers are produced from the epiblast. The cells of the epiblast burrow in to form the endo and mesoderms. The epiblast becomes the ectoderm. The hypoblast is displaced and continues to be part of the yolk sac - It does NOT contribute to the endoderm.
Just commenting here to save this point, and to mark the video. Ty Dr Minass.

aliakberrajani
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Salaams doc, it’s the most amazing lecture on embryology I have ever heard.
Love you for the sake of Allah.

syedtousif
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this was literally the easiest video to understand on embryology! thank you so much

xCrazedHearts
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So much physical efforts to teach someone whom you haven't even seen...God bless u

ashokkumarjaiswal
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this is amazing. i dont understand why this series/your channel didn't blow up more

asserm.
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Please keep making embryo videos! You’re like the only one that I have found that teaches it well and has good illustrations. Maybe Liver, external genitalia, and stomach for the next few videos?

s..u
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Your detailed diagrams and lecture really helped me. I was always scared of development biology but after listening this lecture m nw curious . Thanks a lot sir keep making such videos about embryology.

Nem
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You are definitely created to be a teacher. 👑

anna.banana
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Big thing simplified into little small things easily understandable in very little time, but a huge relief to people like me. I very much appreciate the great effort you put into doing this short yet important video. Hats off to you sir.

beegumhashimuddin
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this is the right platform to start embryology and understand in easy way 👍

kheltaramaarye
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Thank you very much! I'm starting my second year of Naturopathic Medical school in Illinois. It's extremely intense and fast paced. This was a very easy simple understandable way to explain this process. I especially like how you started from the beginning - (sperm & egg). It's easier to follow when you know where everything is coming from (the whole process), rather than bullet points of the stages. You do a great job explaining the whole process in a simple way. Thanks!

vangdavid
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Thank you so much! I have a developmental biology exam tomorrow and you explain it so much better than anyone else!

aylawithers
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This really explained the 2 hour lecture I didn't understand in class, thank you very much for this video, sir.

Frdoskin
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I told myself i would find you after my varsity showed us this lecture video and i did!!😅 you are Literally the best lecture.

AprilKnows
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You're just amazing sir... 🙌❤ THANK YOU SOOOO MUCH FOR MAKING US UNDERSTAND EVERYTHING IN SUCH A SIMPLE MANNER..♥♥

loved the moment when you said, "THIS IS YOU!" 😂🙌🔥

shreyachhabra
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that made my concept clear in just 18 mins. thank you so much sir. the effort you put into your drawing and the colors and explanation...stupendous. thank you again.

sanaalvi
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Just Wow. Literally just wow. Thank you so much!!!! Greetings from Iran

eintroll
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Thank you so much bro.You are amazing.
Now my stress about embryology exam subsides because I found a perfect teacher here!!

alimiri