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Q & A: How do T-cells recognize antigens?
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#immunology #pathology #antigenrecognition
Q: How do T-cells recognize antigens?
A: T lymphocytes cannot directly recognize or be activated by antigens on microbes or those that are extra-cellular in circulation. They are rather programmed to be able to recognize antigens that are presented to it by antigen presenting cells like B lymphocytes, macrophages, dendritic cells or other nucleated cells. Very specifically, T-cells require peptides derived from these antigens to be presented along with certain cell surface molecules called MHC molecules.
Study resources on our website-
References and further reading:
💡Kumar V, Abbas AK, Fausto N, Aster JC. Robbins Basic Pathology. 10th ed. Elsevier; 2018.
💡Kumar V, Abbas AK, Fausto N, Aster JC. Robbins and Cotran – Pathologic Basis of Disease. 8th Edition. Saunders Elsevier; 2010.
💡Abbas AK, Litchman AH, Pillai S. Cellular and Molecular Immunology. 8th Edition. Saunders Elsevier; 2015.
I) Numerous Notes/Cheatsheets and Videos II) Thousands of quiz questions from our vast Question Bank!
HackDentistry is an edtech company that aims make learning dentistry fun,engaging and light hearted.
1) It focuses on helping students understand and retain core concepts in dentistry through highly visual sketch/whiteboard style video animations.
2) The platform helps improve exam performance by providing Revision Bundles and allowing students to test themselves using thousands of Practice Questions from a vast Question Bank. (multiple choice format).
3) It also provides for a community platform where students can come together, and engage with fellow dental students and dentists across the globe!
Facebook:
Instagram:
Twitter:
Q: How do T-cells recognize antigens?
A: T lymphocytes cannot directly recognize or be activated by antigens on microbes or those that are extra-cellular in circulation. They are rather programmed to be able to recognize antigens that are presented to it by antigen presenting cells like B lymphocytes, macrophages, dendritic cells or other nucleated cells. Very specifically, T-cells require peptides derived from these antigens to be presented along with certain cell surface molecules called MHC molecules.
Study resources on our website-
References and further reading:
💡Kumar V, Abbas AK, Fausto N, Aster JC. Robbins Basic Pathology. 10th ed. Elsevier; 2018.
💡Kumar V, Abbas AK, Fausto N, Aster JC. Robbins and Cotran – Pathologic Basis of Disease. 8th Edition. Saunders Elsevier; 2010.
💡Abbas AK, Litchman AH, Pillai S. Cellular and Molecular Immunology. 8th Edition. Saunders Elsevier; 2015.
I) Numerous Notes/Cheatsheets and Videos II) Thousands of quiz questions from our vast Question Bank!
HackDentistry is an edtech company that aims make learning dentistry fun,engaging and light hearted.
1) It focuses on helping students understand and retain core concepts in dentistry through highly visual sketch/whiteboard style video animations.
2) The platform helps improve exam performance by providing Revision Bundles and allowing students to test themselves using thousands of Practice Questions from a vast Question Bank. (multiple choice format).
3) It also provides for a community platform where students can come together, and engage with fellow dental students and dentists across the globe!
Facebook:
Instagram:
Twitter:
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Q & A: How do T-cells recognize antigens?
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