Tandem Mass Spectrometry

Triple quadrupoles are but one form of tandem MS. This video introduces the concept.

[amineabdz]

i laughed so hard at the "Our favourite molecule, cocaine" part

[aliyahremoroza]

Thank you so much, professor! It really helps me in my internship primarily focused on analytical instruments and research on biological samples using mass spectrometry methods. Absolutely grateful that I found your channel and it helps me understand complex concepts that I've been trying to grasp for a long time. And you have summarized it well! Thanks again!

[jl]

really like the way you explain, make it much easier to understand when im not a native english speaker ! thank you so much appreciate your work !

[RohitPant]

I came here out of my course syllabus but i only just now read about your relation to Coach Greg. Whoa! I am now starting to see the resemblance. It's so nice to have came across your channel too. 🙏😊

[RohitPant]

"Let's say you have our favourite molecule now - Cocaine!"
That surely drew me in! 🤣

[bobjoe]

Interesting video, professor. Glad to have learned something new today.

[chewher]

High professor, your twin Coach Greg brought me here. It takes a lot of work and courage to put yourself out there for the world to see. Keep up the good work and best of luck with your channel.

Does Steve edit your vids too?

[merryhere]

I like your methods for teaching makes you want to learn rather than just as a part of coursework

[thart]

Sir thank you so much for all of your time and effort these videos and your channel have helped me so much in my career as a chemical engineer and Equipment specialist God bless you and I wish you the absolute best

[DrumCaptain]

Thank you Dr. Doucette! Very good video I Subscribed

[markhall]

Hey buddy just came here from your brother Gregg’s channel to check your channel out

[XAnyolina]

Thank you very much! Your videos are very clear, keep them up

[samirbrahimi]

Plz sir can u make a video about tandem spectrometry and the use of it in biological or clinical analysis

[deisyvivianasarmientogarzo]

HI!New fan of this channel! Could ypu please let me know if the Precursor Ion Scan can e also done in other Mass spectrometers others than triple quad? how would it be for example in ORBITRAP?

[Ambient_Scenes]

In a triple quad. LC/MS-MS experiment where we set the first quadrupole to only allow the mass ion of the target analyte to pass through, so that it is fragments in the collision cell, will the mass spectrum from the second quadrupole be equivalent to a mass spectrum obtained on a GC-MS single quad system that uses EI ionization? In other words, can LC/MS-MS be used to create mass spectral libraries that can be used for compound identification by EI GC-MS?
Thank you.

[kimtienle]

Some segments in the video are stamped not adjacent to each other

[amandagrell]

Thank you, Very helpful video. Can you explain the difference between ICP-MS and ICP-MS/MS?

[hacko]

Hello. I would like to ask you for advice. Does the mobile phase have a major effect on the optimization of the mass spectrometer? When optimizing the mass spectrometer, I chose a mixture of acetonitrile and water as the mobile phase. However, when optimizing the HPLC method, I chose a mixture of buffer and methanol as the mobile phase. I would like to know if the change of the mobile phase has an effect on the mass spectrometry (finding of precursor and product ions, voltage of ion optics and collision energy)

[shadeedsalem]

Question; what is the ideal lc-ms/ms in the market for therapeutic protein characterization right now? Thanks

[ramankumarlaldas]

kucch samajh nahi aaye chee. ek to pehle se hi kucch nahi hota, upar se aur sab upar se jaaye chee