Celiac Disease | Clinical Presentation

What is Celiac disease? Celiac disease, sometimes called celiac sprue, is a condition where the immune system reacts to gliadin, a component of gluten, which is found in various grains like wheat, barley, and rye. This video covers the known pathophysiology, as well as important clinical signs and symptoms

[sanaali]

Thank you osmosis for making it so easy to understand while describing all the details❤

[DrAdnan]

Osmosis is one of my favorite study video resources!

[lama-]

Best explanation for celiac disease ever

[m.b]

Tbh, this one is Better than the 2021 edition

[JHT]

I do have muscle related symptoms when I have gluten crosscontamination, you said in your video that there is no symptoms, but I do have them, within minutes of ingestion, I don’t know how to describe it, but it seems that my entire skin and muscles start feeling heavy as lead, it’s very difficult, no energy whatsoever, feels like dying; you sleep well at least.

[draanapimenta]

First time seeing this film! It seems like I am drawing to explain the disease to my celiac patients or their relatives! Thanks!  a good link to send to them!

[TheBigBrainBusters]

Something interesting on why CD8+ cytotoxic cells are recruited as well is because, the deaminated gliadin peptides tend to induce production of IL-15, from the epithelial cells which cause epithelial damage, and in addition, the epithelial cells subjected to so many stressors end up expressing MIC-A molecule which is recognised by NKG2D receptor of the CD8+ T cells, thus further exercerbating the enterocyte damage

[lakshayrana]

Explained in an awesome manner but the video is a bit blurred and hazy

[zack_]

0:50 - the endosperm part comprises largely starch and some proteins, not vitamins and minerals which are mostly in the bran layer that encloses the endosperm and germ. This is why eating whole grains is being promoted.

[bootatoboo]

celiac disease is also a common cause of iron deficiency anemia, i was hoping to find out the mechanism but im guessing the destruction of enterocytes containing transferrin receptor (due to cytokines released from T-cells) causes there to be less TSR hence decreasing the absorption of iron. if im wrong please correct me.

[francescopentangelo]

you bro, you are a so good boy. thanks for that video

[meepmorp]

Having Celiac sucks but it is better than peanut allergy, I don't have a high risk of dying if I accidentally consume gluten but it will be a pain later on

[ingridmazariegos]

What app is used to create animated videos like this? I love it

[leavesofchange]

Would the mechanism work exactly the same if you substituted secalin for gliadin?

[AuroraLakes]

1/3 of the population is expected to have it. If you have ANY Northern European DNA there is any 85% chance of you have it.
The reason little is known is because of the WFAOA Wheat Farmers Assc of America. In the 1940's they lobbied to have it quit being taught in the USA. They got their wish. From 1954-2004 only a single paragraph was dedicated to Celiac disease, and in that 50 years not a single word in that changed. That is why most Drs have no idea what the symptoms look like. I suffered for over 23 years until it turned into Duhring disease. I am self diagnosed after going to 5 different Drs. I am retired from medicine, and finally healthier than I have been in decades.

[badnewssourgrapes]

I have celiac for about 5 months now still having problems even though I eat gluten free still having lots of mucus when I wipe no blood though so tired of being sick all the time it's affecting my work👎

[piyasaini]

CAC Curcumin capsule is prepared from the herb turmeric. The herb turmeric (Curcuma longa) contains the active compound curcumin that shows antioxidant, anti-inflammatory, analgesic, & immuno-modulator properties. These properties deal with the pain in abdomen, loss of appetite, indigestion, & improve overall digestion. It helps in building up the immunity of the small intestine to deal with the coeliac condition.

[andrebantolo]

does glutenin have the same affect that gliadin does?

[SlayAlison]

Coeliac disease is so annoying like there’s not many foods at my school I can eat

[nooralhoda]

can anymone help me ? i have a question : in normal case for people who don't have celiac disease do they don't absorbe gluten ?