More tips for 1st Time IVF Success

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I have been getting a lot of Email from patients asking for more tips to increase their chances for 1st time IVF success. Here is our 2019 edition

#IVFSuccess tip 1
Optimize the stimulation of the ovaries - To get the best quality eggs, the ovaries need to be stimulated with two different hormones - FSH and LH. FSH is the hormone found in medications like Follistim and Gonal F. Either of these medications will work great for your IVF protocol.

IVF protocols that combine FSH and hCG may work better than FSH and LH. So ask your doctor for the low dose hCG protocol. Oh and one other advantage, hCG is a lot cheaper so you can save a few thousand dollars in medication costs

#IVFSuccess tip 2
Use the right kind of progesterone. You already know from our last video on first time IVF success that you should be doing a frozen transfer instead of a fresh transfer. To do a frozen embryo transfer, you first prepare the uterus with two medications - estrogen (to get the lining thicker) and progesterone to make the lining receptive to an embryo. It does not seem to matter what kind of estrogen is used. It can be oral estrogen, vaginal estrogen, estrogen patches or even estrogen injections. Doesn’t matter.

The type of progesterone does matter however. This last year, a study was presented involving about 1000 women who were doing a frozen embryo transfer. They were split into three groups. Group 1 took vaginal progesterone only. Group two used vaginal progesterone and a daily injection of progesterone. The third group used vaginal progesterone and a progesterone injection every three days.

What they found is that the group using vaginal progesterone only had lower pregnancy rates. So much so that they stopped adding patients to that group even before the study was over. There was no difference detected in whether injections of progesterone were added every day or every three days.

So for this tip make sure you are taking both types of progesterone. Vaginal progesterone every day and injections of progesterone every 3 days

#IVF success tip 3
Timing the embryo transfer. It turns out that not only does it not matter what type of estrogen you use, it also doesn’t matter how long you take the estrogen. The amount of time for progesterone however is very improvement. Progesterone changes the uterine lining to make it receptive to an embryo. For most women, the optimal time to place a blastocyst stage embryo into the uterus is on the 6th day of progesterone. There are some women, however, where the timing is different. For those women, it might be better to put the embryo into the uterus before or after the 6th day. To determine the correct timing, we need to do a test called an Endometrial Receptivity Array or ERA. To do this test, a woman must take her estrogen and progesterone the same way she would if she was planning to do an embryo transfer. But, instead of doing an embryo transfer, her doctor will take a sample of her uterine lining for the ERA.

Not all women should have this test before their first attempt. This test is best for women who have already have had multiple failed transfer attempts. However, there are some circumstances in which it might make sense to do it before a first attempt. Women who are obese, with a BMI over 30 have a higher rate of timing problems. They should consider the ERA before their first attempt. Another group would be couples who only have one embryo for transfer. Just to do everything to maximize their chances for what might be their only attempt.

OK there you have it, three new tips for maximizing the chances for first time IVF success.

Infertility TV is your weekly source for the best medical information if you have infertility, recurrent miscarriage or are just trying to conceive. (TTC). InfertilityTV covers infertility testing, fertility treatments such as Clomid, Follistim and Crinone and fertility treatments like IUI and IVF (in vitro fertilization)

One of the most popular playlists on InfertilityTV are the TTC tips which are great even you are not struggling with infertility

Dr Morris is a practicing IVF and infertility expert who sees patients at IVF! located in the Naperville Fertility Center.

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My 1st ivf got successful.... M soo Bless me...

meenaximalipatil
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Thank you for the videos, especially the videos on ivf success tips . I conceived and gave birth to a baby girl on 13 Aug after 36 weeks. It was my second attempt at ivf. Your videos showed me the path during the second cycle and now I have a beautiful baby girl !

CatherineCarol
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I didn’t succeed the first cycle because I didn’t watch your videos. After Watching the videos and insisted my RE to follow your advice regarding estrogen and progesterone intakes. Now 12 weeks. I am so glad you share your knowledge through these videos.

CatherineCarol
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My first transfer worked due to your advice on diet and medicine, and treatment. Thank you doctor!

crystalmorse
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My IVF got successful, bless me, god gve me opportunity to take roles as mother, today embryo transfer for second, wish me luck

faezah
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Thank you Doctor for the information. Really appreciate it.

inthemaking
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Thank your for sharing your expertise doc! You are so generous.May the Lord bless ur heart .You are hope to every TTC like me.

cecilnuga
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Thank you so much for taking the time to spread such useful information.

rihamturk
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O lord please let me have a successful IVF after 45 ! Please no judgment on age !

meredithposeyjohnson
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thank you so much doctor for this very useful information. I am preparing my first IVF now.

hasnihasan
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We need a healthy child please need 1st time IVF success

maheshmutreja
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ngiyabonga Dr, I will introduce these to my fertility specialist, especially the Estrogen and ERA because I have a history unsuccessfully IVF. now i am going to try with a donor egg

noxolosakang
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I requested to everyone plz pray for me
My icsi treatment is going on.

AAA-zgvu
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Hi my age 47 did my ova retrieve in Thailand in January i got 1 healthy embyro now waiting for emb tranfer plz give me tips for success

shizashahid
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All of your videos are very informative but i got to say that background music is very loud making it difficult to understand. Just an advice for the future videos.

firuzeakbulut
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I just did my egg collection procedure just yesterday. Thinking of safe way and success to transfer my embryo...

suhaymar
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I have my fist transfer in a few weeks and I am so scared but hopeful

kittykat
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Dear Dr., please can you please do a video about second time Ivf treatment and how to prepare for it .

jajajohnson
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Can you please provide the study of progesterone? I would like to send that to my doctor. They want to do vaginal only progesterone

sunshineNshit
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Thanks doctor. This is very important and useful! My wife and I failed at first time of IVF. She took only Menopur when stimulating and got only 2 Embryos. She did s fresh transfer with only vaginal progesterone and without ERA, so it failed. After several months for the transfer of second embryo, it broke in the defrozen progress! How bad luck we were! Now we do the second stimulation and we only get one embryo and we decided to wait for another frozen transfer. Do you have any suggestions forces? Many thanks doctor…

thinkerdoer