Nuclear Localization Signals and Import | Cell Bio | Video Textbooks - Preview

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Proteins imported from the cytosol to the nucleus contain short stretches of amino acid sequences called nuclear localization signals or NLS.
Importins, specialized nuclear import receptors, recognize the NLS of cargo proteins and transport them to the nucleus through the nuclear pore complexes or NPCs.
Importins are present in the cytosol as soluble dimers of an alpha and a beta subunit.