Nuclear Import and Signal Hypothesis

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Cell biology tutorial about protein transport to and from the nucleus.
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I'm so happy I found your channel x

mrsdiggory
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What happens when the cargo is released? Does something come along and actively transport it to where it is needed or does it just go by Brownian motion?

LAGoff
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Can you explain how the importins carry the large molecules across the sieve? Are the fibres hydrophobic or something? Do they clear way for the other molecules?

hareeshscifi