Human growth hormone (HGH) for longevity: Does it slow aging? | The Peter Attia Drive Podcast

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About:

The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 40 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more.

Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life).

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[joshuacrow]

I had a failed fusion at L5-S1 in 2011 at 31 years old. By 2012 my doctor said the fusion did not fuse, referred me to a pain clinic, took me off work and had me apply for disability. I could not live on the tiny disability check and put all the money making on my wife’s shoulders. I was and continue to do bodybuilding time to time. So my gym connect said he knew an AIDS patient that got like 32iu of Serostim a day and needed money. Think I paid like $200 for over 100iu and took it at 3iu a day for 3 months. When I went back to the surgeon and got a MRI and CAT scan with contrast he couldn’t believe it had fused. He still said no leg or ab training. I was built funny with big upper and little lower body so I broke with his rules and started squats and deadlifts. Needles to say I’m pain free and show up the young bucks at the gym and I’m 43. So I’m a believer in hgh.

[samoconnor]

I shattered my ankle into literally 50 pieces, compound on both sides, tib/fib fracture with separation, and torn MCL. Had the best orthopedic surgeons arguably in the country... was told I would walk with a limp for the rest of my life, which was a blessing considering amputation was on the table. Ran a very aggressive peptide protocol of TB 500/BPC 2Iu of HGH, and Test/NPP and a few low/short Anavar/Primo cycles with my TRT, and my entire team was dumbfounded at how much my body healed after the natural state. MRI showed cartilage, regrowth, tendon/ligament and joint repair, and possible bone growth. To say it was a lifesaver would be an understatement. It's unfortunate that these treatments are not more readily available.

[mattarndt]

I think the guy said it, that what is good for older men, may not be good for younger men. I think the problem now a days is men in their 20’s and early 30’s are on TRT, Hgh and other PED’s. Have they been tested prior to doing so? I will be 52 this year. I don’t think I would try these things in my twenties. Now I actually need them. Also, I don’t buy into how the hormones extending our lives. I think it’s more about improving what life I have remaining.

[myhumps]

When I broke my leg, I took HGH, testosterone, Robitussin, and ate chipotle every day. My leg healed in two weeks.

[dr.elenazinkov]

We need to differentiate between HGH and GHRH and GHRP. If growth hormone peaks in our twenties and declines 15% every decade, we can stimulate it’s release (and not daily like mentioned) in amounts 100-200 mcg 1-2 times per day also depending on the peptide (not sure where the 1 mg dose came from). In terms of longevity—growth hormone decline is one of the contributing factors for poor sleep and impacts deep sleep. And we know that lack of sleep is one of the contributing factors for neurodegenerative conditions.

[gabepeterson]

Side effects:

Improved cholesterol
Decreased body fat
Increased lean muscle
Improved sense of well being
Increased telomere length

BAD STUFF FOLKS!!! PROCEED WITH CAUTION 😂😂

[majuscule]

It's been like five times I subscribed to this channel and I never did unsubscribe even once.
I would never miss a video from Dr Atta, even accidentally. Have anyone experienced the same problem?

[yashvardhansinghsolanki]

Id rather live happier and live till 70 than geriatic and aging at 99

[Nobody]

As a 62 year old male user of gh. I have had fantastic results with it. In combination with exercise and diet. I have had five spinal surgeries and two brain surgeries. Could not walk for several years. Much better now.

[bryceherring]

I think its pretty clear that the use of growth hormone for anti aging and longevity is not going to kill any patients or radically increase their chance or death, I noticed Peter mentioned this in the first part of the clip. GH and other hormones' that ones body can produce naturally and we should all strive and hope to increase our own production endogenously by use of best practices like sauna and deep sleep which both trigger strong releases of GH, however, if your an older person and are struggling with health, adding in GH would certainly help, the problem is, just like adding in other external hormones, does your body shut down or decrease its own production of some of these vital hormones if an patient decides to start supplementing with them exogenously via shots, creams or oral supplements?

This is why young, healthy people should not all of a sudden start adding in anabolic steroids or sex hormones, sure it would be nice if I had ramped up or increased testosterone production but that's also gonna slowly and negatively impact my body's own natural production down the line. Any red blooded, muscle wanting American male would love the benefits of more T or GH as these are the super human mega pump hormones that add to our quality of life, but most guys should focus on ways to naturally increase or maintain their own levels vs switching to outside shots or injections.

[BOULDERGEEK]

This is a question I (56M) have been researching (layman) for 20 years. We all want to prolong our vital years, and why not start better living through chemistry if one could? But, there are a lot of wive's tales. I appreciate this professional discussion to disabuse me of some of my preconceptions and discuss the state of consensus on this topic.

[jimmiers]

I like big concepts. When things get too molecular I just wonder if the researchers are off in silly land. For me its simple, if aging is an atrophy disease and it is, anything that arrests this should help our prolong our eventual demise! There have been some incredible things reported for severe head/ nervous system damage using Growth hormone.

[Sinasi]

You should invite Dr Thierry Hertoghe in the podcast, specially related to bio-identical HRTs (Growth hormone etc).

[gamblinguru]

No discussion of Dr. Fahy's work using intermittent growth hormone administration to regrow the thymus? This would almost certainly have an anti-agingj effect.

[juliebrady]

Im a 54 year old Female. Despite being active, 5 days a week and 3 hours per day at the gym, I DID get sarcopenia at the age of 52 years.
Id really love to see those studies you spoke of that found women with low IGF arent any more likely to get sarcopenia than women with normal levels. 😅😅
The truth is, you CAN live to be 100 years old, and beyond, with sarcopenia, so how can you suggest the reason women live longer than men is because they dont beed IGF the way men do...
Correlation does not equal causation dude.
As a doctor, you should know this.

[sokaiya]

regenerates Thymus gland. Major effector of the adaptive immune system aging. T cell incompetence is a major cause of age-related morbidity and mortality!!! Therefore, the goal is to reverse thyme involution. Mortality rate goes up and immune system function goes down as we age because our Thymus degenerates with time.  After puberty it already starts shrinking and making less naïve T cells.  And that is why you see cancer in people over 50 but not in kids.  That’s why people die of the flu in old age but not children.

[johndamascus]

I don't get the "confounders" point. This is a case where singling it out doesn't necessarily matter. If you are willing to take HGH, you also do other things - yes, we can't see necessarily it as an independent to study, but we can see that the people aren't giving the "dying signal" Dr. Attia is asking about. At a minimum, the negative effects therefore wouldn't be big. Again, we already know that there is nothing in the world that is ALL benefit, so this is helpful to know, since it suggests that HGH therefore isn't crazy dangerous.

[angiemasse]

Very informative video. The answer is " We dont know that "

[tabularasa]

BPC-157, Ipamorelin/CJC-1295, HGH for 8 weeks post orthopedic surgery should be considered. Also, eating in a calorie surplus with increased fat and protein should be considered post surgery combined with increased exercise.

[jwwilliams]

Of course the females who didn't use gh lived longer. They didnt do shit. We need to consider quality of life not just length.