Central dogma of molecular biology | Chemical processes | MCAT | Khan Academy

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[ellierome]

No, actually it was Franklin that discovered DNA. Her problem was that she openly shared her notes not knowing how W&C would later publish and take full credit for it. In fact, Franklin studied the discovery of Frederick Meischer to be exact. But his findings weee not understood even by him although he was on to some and just never finished. But Franklin sort of brought his discovery to life and she was the one that said there is no triple helix but only a double. So this Watson And Crick duo basically stoked info and won a Nobel prize which by then, Franklin died. So messed up.

[leonafriedman]

Its a shame that the makers of the video are crediting Watson and Crick, who stole the findings of Rosalind Franklin. By the time they won the Nobel prize, she had unfortunately already died.

[togohogo]

simple. Translation comes after transcription in the dictionary. Thats how i remember it.


BTW: they are all in alphabetical order :P

[hosamfikry]

I love the last part! I was always confused between both of them

[shayana]

@2:35 I was under the impression from prior learnings that we don't have a reliable system yet for predicting tertiary protein structure based simply on the DNA, RNA, or primary amino acid sequence.

[emmanuelofosu]

Transcription has a C and Translation has an L. C comes before L in the alphabets. That’s one way to remember.

[SyedSufiyan]

The neatest handwriting I have come across. :-) And I sat through the entire 4 minutes 21 seconds just because of the hand writing and the voice. :-)

[christymathew]

Wow. This is really helpful. The way you teach like using script and translation in language kinda things to remember, that was good. I actually know this process but I confused or sometimes I mixed up translation and transcription. This lecture help me alot. Thanks☺️

[darrenerickson]

So I really don't know - I'm reviewing this as part of an exam - but Wikipedia also lists three special cases of transfer as part of the Central Dogma which only happen under certain conditions. RNA can reverse-transcript DNA in some retrovirus cases, RNA can transcript itself in some cases (viruses, ) and under lab conditions DNA can directly translate to proteins. The other paths (Protein->RNA, Protein->DNA, Protein->Protein) are unknown to exist. Is that also part of Central Dogma, even if it is usually not part of a Freshman Biology class?

[selfull]

"Dogma" has forgotten one thing, I believe; if genetics has an impact on everyone, then everyone has an impact on genetics.
If genetics/DNA can be calculated in time, then it implies that there is a beginning to it. Where is it coming from then?
Opposing itself would be a logical way to describe it.
Then RNA/epigenetics would be valued by single life experience and their environment then transferred/transcribed genealogically as DNA, at a value requirement that is above my current understanding but to which I am researching towards and which would logically be fulfilled in either time/generations or value/new life experience.
If changes in time can be noticed in DNA, then changes in our time will be seen in our successors one (our kid's one), later on.

What is needed is to figure out "how" this mechanism works, exactly and how someone could show it like it's been demonstratwd in animals and nature, before. I would like to know if anyone has an input on that. People seems to inherit a bigger part of their RNA/DNA from their grandparents rather than their parents but all awhile inheriting from them too, without a doubt. Like it can been seen in nature and animal kingdom with the fibonacci sequence, for example.

What I'm trying to say is that a plant's leaves don't grow all on one side and skips a level to balance itself, having for effect that if a "fuck up" happens, it doesn't go downward spiral from that point on, leading towards an imminent failure. It balances itself and carry on. That seems to be the same mechanism that happens in human's genetics but has never been demonstrated before. If I take myself for example; being 6'1 and both my parents being under 5'5, it is clear that I did not inherit that from either of them. All awhile I did, without a doubt, inherit values from both. Same goes for most of my cousins.

Is there a way anyone could think of, to prove the variations brought by a single value/life experience?


Side note
I believe RNA is being transcribed in the amygdala, more precisely and that's due to a couple facts that I have logically correlated together; we share the subcortical brain with mamals and if you take Australian sheppards dogs, for example, which we share that part of the brain with; this dog has been breed to herd other animals on farms, for long enough that new born coming from families that haven't been used to herd on farms, for many generations are born, today with that skill that their ancestors have been taught, right at birth, as if it was “instinct”.

Meaning that there is a transfer of memory being made subconsciously. Behaviors as such can been observed in many breeds of dogs like Labradors, for example, in which physiological changes can even be noticed wth their webbed paws and enlarged tails to facilitate them swimming and navigating in water and which have been breed to help fishermen in Newfoundland Labrador, Canada, less than 200 years ago.

Also because of the differences in male and female brains and the difference in their lifestyle, in history. The man living a more nomadic and eventful life, required to pass down more information than the women who lived a more routinely and sedentary lifestyle. Staying in safe and known environment, therefore requiring less new experiences or trauma to be passed down, explaining why the amygdala is bigger in male and smaller female brain. That would explain the inheritance differences between both sex, as well.

That's where I'm at right now and what I am currently researching but I found out that male and female hormones, estrogen and testosterone plays a big role too, which correlates with both sex's insulin tolerance and metabolism.

As men grows older, they deplete their testosterone hormones up to andropause; their insulin resistance increases in association with increased triglycerides and decreased HDL cholesterol(good cholesterol). And as women grows older, they deplete their estrogen hormones up to menopause; their insulin tolerance decrease in association with decreased triglycerides and decreased HDL. The exact opposite but which is the point where inheritance of illnesses and disorders are the same in men and women.

Meaning that: More testosterone = less insulin tolerance, more LDL(bad cholesterol), and transferring more genetical variations.
And that: More estrogen =more insulin tolerance, more HDL(bad cholesterol), and transferring less genetical variations.

Im getting close but if anyone has input on that, too, I'd love to discuss it with anyone who grasp the concept and who's knowledgeable since I have only carried studies of my own, based on scientific researches.
Thank you.

[Simon-]

This is nice, effective and simple. Saved me a lot of time.

[devnayak]

plzz upload Beedle &Tatum studied central dogma in a fungus Neurospora.

[comedywithpuku]

Very good Video but RNA to DNA by the process of Reverse Transcription should be included(LIKE if understand)

[yegoddessyegoddess]

What about the Ancient-Africans who created and put all of this together, before Rosaline, Watson, and Crick came to discover or break down something that already existed???

[izsjxhs]

In turkey we learn this at the freshman year of high school, i am surprised that it is in med school too

[deisykevelinloboreyes]

I like your video but I do not know much English. I am in basic 7 just. Please put subtitles in Spanish

[djendellehazelcaballes]

how could she have a hand like that? like did she just use a mouse to draw and write all of that?

[zainabb.]

Thanks a lot! I hope more females show us their ability and explain things more often.

[lm]

Doesn't RNA also replicate itself?

[nickolausafon]

I need a serious genius woman to help me right now. Khan did not help me last time. It did not gear me to the nature of the Test or half the material. It's hard to memorize.
*Welll. I think I need to practically cheat because the knowledge and the grade are my aims, but I don't. "It can be kinda tricky to keep all these terms straight."
*** I want to get an A on this test. I need to have strong memorize facts and know how to problem solve. It takes appropriate information and knowing when to use it.