Central Dogma of Molecular Biology || Central Dogma of Life || Biochemistry

Central dogma of molecular biology : The flow of genetic information from DNA to RNA to protein in living cells is called the central dogma of molecular biology
Central dogma of molecular biology was formulated by Francis Crick.
Central dogma of molecular biology comprises of three major processes
1. Replication
2. Transcription
3. Translation

[majrooh]

Superb video. This is short clip but enough for everyone. Thank u sir

[hebaaldossary]

Thank you Dr Amit. That was very clear explanation

[selfull]

"Dogma" has forgotten one thing, I believe; if genetics has an impact on everyone, then everyone has an impact on genetics.
If genetics/DNA can be calculated in time, then it implies that there is a beginning to it. Where is it coming from then?
Opposing itself would be a logical way to describe it.
Then RNA/epigenetics would be valued by single life experience and their environment then transferred/transcribed genealogically as DNA, at a value requirement that is above my current understanding but to which I am researching towards and which would logically be fulfilled in either time/generations or value/new life experience.
If changes in time can be noticed in DNA, then changes in our time will be seen in our successors one (our kid's one), later on.

What is needed is to figure out "how" this mechanism works, exactly and how someone could show it like it's been demonstratwd in animals and nature, before. I would like to know if anyone has an input on that. People seems to inherit a bigger part of their RNA/DNA from their grandparents rather than their parents but all awhile inheriting from them too, without a doubt. Like it can been seen in nature and animal kingdom with the fibonacci sequence, for example.

What I'm trying to say is that a plant's leaves don't grow all on one side and skips a level to balance itself, having for effect that if a "fuck up" happens, it doesn't go downward spiral from that point on, leading towards an imminent failure. It balances itself and carry on. That seems to be the same mechanism that happens in human's genetics but has never been demonstrated before. If I take myself for example; being 6'1 and both my parents being under 5'5, it is clear that I did not inherit that from either of them. All awhile I did, without a doubt, inherit values from both. Same goes for most of my cousins.

Is there a way anyone could think of, to prove the variations brought by a single value/life experience?


Side note
I believe RNA is being transcribed in the amygdala, more precisely and that's due to a couple facts that I have logically correlated together; we share the subcortical brain with mamals and if you take Australian sheppards dogs, for example, which we share that part of the brain with; this dog has been breed to herd other animals on farms, for long enough that new born coming from families that haven't been used to herd on farms, for many generations are born, today with that skill that their ancestors have been taught, right at birth, as if it was “instinct”.

Meaning that there is a transfer of memory being made subconsciously. Behaviors as such can been observed in many breeds of dogs like Labradors, for example, in which physiological changes can even be noticed wth their webbed paws and enlarged tails to facilitate them swimming and navigating in water and which have been breed to help fishermen in Newfoundland Labrador, Canada, less than 200 years ago.

Also because of the differences in male and female brains and the difference in their lifestyle, in history. The man living a more nomadic and eventful life, required to pass down more information than the women who lived a more routinely and sedentary lifestyle. Staying in safe and known environment, therefore requiring less new experiences or trauma to be passed down, explaining why the amygdala is bigger in male and smaller female brain. That would explain the inheritance differences between both sex, as well.

That's where I'm at right now and what I am currently researching but I found out that male and female hormones, estrogen and testosterone plays a big role too, which correlates with both sex's insulin tolerance and metabolism.

As men grows older, they deplete their testosterone hormones up to andropause; their insulin resistance increases in association with increased triglycerides and decreased HDL cholesterol(good cholesterol). And as women grows older, they deplete their estrogen hormones up to menopause; their insulin tolerance decrease in association with decreased triglycerides and decreased HDL. The exact opposite but which is the point where inheritance of illnesses and disorders are the same in men and women.

Meaning that: More testosterone = less insulin tolerance, more LDL(bad cholesterol), and transferring more genetical variations.
And that: More estrogen =more insulin tolerance, more HDL(bad cholesterol), and transferring less genetical variations.

Im getting close but if anyone has input on that, too, I'd love to discuss it with anyone who grasp the concept and who's knowledgeable since I have only carried studies of my own, based on scientific researches.
Thank you.

[ashritaray]

Thank u so much sir for your clear explanation 🙏🏻very helpful..

[gulfwarveteran]

Sir pls make video on metabolism of xenobiotic s 🙏