Cyclin and CDK in cell cycle progression | How Cyclin CDK works?

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[zhansayabauyrzhanova]

Omg, I m rewatching and realizing that u explain much better than professors. Thats the fact. I found hard to understand before. Now, I feel like I got at least for 80% thanks a bunch again! u made my life easier!

[breadyogurt]

One question - what is the role of CyclinA-Cdk2? Why is it needed in S phase, if CyclinE-Cdk2 phosphorylates ORC and Cdc6 to prevent re-replication and initiates replication by activating Mcm2-7?

[golamrabbani]

Concept is more clear with the animation 👍
Thank you sir ❤

[elenachatz]

I love your videos, everything is so well explained. Thank you very very much for your work❤

[zhansayabauyrzhanova]

do u have classes to make graphical visualization? How did u learn, yours are soooo beautiful and easy to understand! Thanks a bunch!

[samiullahsyed]

Sir do you know where I can find advanced problem sets over content from Alberts Molecular Biology of the Cell and Lodishs Molecular Cell Biology?

[ckyqiuu]

It is true that cyclin must have a specific concetration in order to bind with Cdks or as the concetration of cyclins rises also the formation of the cylclin-cdk complexes rises?

[HasanbasriAkkaya]

11:10 we were talking about cyclin E CDK2 but you put Cyclin B CDK1. If it’s a mistaken or not????

[ophthojooeileyecirclehisha]

thank you for you hard work information and kindness

[zhansayabauyrzhanova]

Also, Cyclin D-> E2F -> cyclin E -> cdt1, .. S proteins-> ? -> cyclin B

[zhansayabauyrzhanova]

replication happens once, not twice, why?

[zhansayabauyrzhanova]

what s the role of cyclin D in pRb binding ?