Thyroid Hormones and Thyroid Function Tests

An overview of the synthesis, regulation, and function of thyroid hormones, as well as the interpretation of thyroid function tests.

[kalldagreat]

Please keep on making these videos, you have no idea how much it has helped people from around the world!! I just want to express my deep gratitude to your unconditioned contribution!! Eric's Medical Lectures

[cypress]

The clearest and clinically most relevant thyroid video I've seen on YouTube.

[thomaslau]

The best presentation on the clinical aspect of Thyroid gland problem I come across so far. Thanks.

[sunving]

Thank you very much Doctor Strong! You do a great contribution to many medical students, interns, residents, junior or not so junior doctors around the world.

[damnyeahnich]

Amazing! you've saved me hours of reading and understanding on my own! Thank you!!!

[irfankhan-rkyd]

13:20, you had me here, where you said "differentiated" thyroid cancers... attention to detail is just amazing.. reason behind it is the fact that, if you follow-up a patient with undifferentiated malignancy, thyroglobulin will not be increased.

[kalravjoshi]

BIG THANKS SIR. I AM A GENERAL PRACTITIONER IN INDIA. THIS SUBJECT IS ALWAYS CONFUSING AS TO UNDERSTAND FORM MEDICINE BOOKS LIKE HARRISON OR DAVIDSON. THIS VIDEO HAS CLEARED ALL MY CONCEPT NOW I CAN UNDERSTAND AND TREAT PATIENT VERY CAREFULLY AND PERFECTLY.

[MikeBirkhead]

Subtle (probably unimportant) correction:
Wolf-Chaikoff effect refers only to the decreased activity of TPO in by iodide states. Several theories exist on why this occurs.

From my short glance at the literature, my understanding is as follows

There are three effects (including wolf-chaikoff) that make high iodide useful in hyperthyroidism.
1. It can inhibit TSH signaling (most likely via inhibiting the GPCR)
2. It can saturate the sodium iodide symporter (which is mechanism of protection from radioactive iodide).
3. Wolf-chaikoff effect -- inhibition of TPO activity (possibly by reducing peroxide levels -- perhaps through inhibition of NADPH-oxidase)

It's also important to know that all three effects that work together to reduce thyroid hormone levels are subject to "escape" by a healthy thyroid after about 10 days. This is due to downregulation of the sodium iodide symporter, which reduces total intrafollucular iodide, thereby releasing from iodide inhibition.

[viraltiktokviraltiktok]

NEVER HAVE I SEEN A VIDEO THIS CLAER, THANK YOU SO MUCH DOCTOR, AM A CUBAN TRAINED SOUTH AFRICAN STUDENT
AND THIS HAS HELPED ME

YOU DESERVE MY SUBSCRIPTION...GRACIAS.


STANFORD MLAMLI TIBE

[poonamchoudhary]

I really wish to see more n more of such crisp, correct n precise info..thank you so much for posting such a productive content

[mustafacekmen]

Thank you. Exxellent video. Dear Dr. I am Dr. Cekmen.M. from Turkey I am MD and PhD. At the about 9. minute of presentation, You said that ''cold stress can effect negative (-) on the TRH and TSH''. I know that ''cold and emotional stresses stimulates the synthesis or releases TRH and TSH''. Is it possible re-evaluation Please.

[naveenbabu]

Life saviour for clinical investigation interpretation..
Thank for contribution sir

[Electronics]

Greatly appreciate and thankful for very detailed video on Thyroid conditions

[dr.md.shalahuddin]

Dear doctor Eric Strong. I am a medical graduate from Bangladesh. I must admit that your videos helped me immensely. Undoubtedly they are of high quality. But I have some questions. I will be highly grateful if I got the answer:
1. What is the mechanism that ESS causes so many patterns?
2. Would you please tell me which drug causes what change & how?
I know if you answered those questions in the video, it would be a long one as well as boring. But I think it isn't so here.

[cocokrisp]

I really liked this video! Very clear voice and explanation. So helpful! Thanks!!

[petercourt]

Very thorough and complete. Many thanks.

[mbulawandala]

I nearly got discouraged, but going through comments section, I then realized I'm not the only one who noticed- cold stimulates TRH release, and so does stress(emotional and physiological)

[jagjeevandeshmukh]

Great explanation in simple & easy way with all clinical information
🙏🙏

[drpadghan]

Very clear and concise information 👍👍👌

[thyroidhealing]

Love your video! I have started following a diet for 90 days which will completely cure Hypothyroidism if I follow it the right way. It may take longer than 90 days dependant upon how severe my condition is. I am on thyroid meds for 13 years now and I can't wait to take them off any live my life freely with full of energy and zeal!