Hyaluronic Acid: Does it Reverse Skin Aging? [Study 109-116, 120-122 Analysis]

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0:00 - Introduction.
1:29 - Topics Covered.
3:02 - Study Backgrounds.
5:34 - Skin Physiology & Hyaluronic Acid [Study 121, Study 122].
15:15 - Injected Hyaluronic Acid.
15:27 - Study 112.
23:34 - Horrible Meta-Analysis [Study 114].
35:42 - Topical Hyaluronic Acid.
35:48 - Study 109.
45:40 - Biased Study [Study 116].
50:10 - Study 121.
54:12 - Oral Hyaluronic Acid.
54:17 - Study 110.
1:03:56 - Study 111.
1:08:20 - Study 113.
1:10:37 - Conclusions/Take Aways.

Note: The information provided in this study analysis is limited to the subject and outcomes detailed in the study analyzed [For example: “Consuming sugar (subject) raises insulin (outcome).”] and is not meant to be an all-encompassing education on every health outcome of the subject (unless otherwise stated). I welcome all respectful critique of the study as I may have missed a key detail that you may catch; if that is the case, I will make an ‘Amendment’ to the video and credit you (thank you for making science knowledge better!).

If your comment is rude, not about the study at hand (i.e. extending to other outcomes not discussed), or critiques without a scientific basis – your comment will either be ignored or deleted. If you post a scientific study (in support, or to refute, the study at hand), please post the DOI number, since YouTube automatically removes URL links. Thank you!

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#skincare #agereversal #agingbackwards

[Physionic]

I've been taking hyaluronic acid for 1 day and my 98 year old skin looks like new!


*This is an affiliate link, and I have no relationship with the brand.

[BT-vhlz]

You are our beloved NERD . I was looking for someone who willing to juice out their brain cells by reading the research articles, analyzing the methods/results/charts/data/conflicts, AND drawing unbiased conclusions on them. I'm finally done with my search . YOU ARE THE GUY [now imagine yourself glowing] 🌄🌅. I frequently surf JAMA, PUBMED, NCBI, and ScienceDirect, but lately, I just don't have the time to finish reading them all. I also appreciate how calm, patient, and ridiculously smart you are at describing complex mechanisms and tackling difficult subjects. Keep it up!!!

[garyr]

I can’t express how valuable your channel is
Your approach
Style
Hard hard work
All here for us
Incredible really
Thank you

[rtnjo]

I really enjoy this lengthy video format! Thank you for your hard work!

[kenhnsy]

I got the B, then C correct. But the lighting also looks different in intensity. I remember reading about a pinch test. Pinch your back hand skin for 10 seconds and time the return to flatness, Unscientifically, oral ingestion of HLA and vitamin C obviously improved my skin in one month. Relaxation time of my skin went from around 5 seconds to less than one second.

[tootstoyou]

I’m 70 F. I used HAcid topically for quite a long time. Didn’t really see the benefit. Recently, started glopping my face, arms, knees and feet with high quality pure CASTOR OIL (in a dark glass bottle). Big difference! My skin absorbs it like crazy, looks and feels substantially better!

[Shiv]

Hydrolyzed collagen with all peptides also is needed with hyaluronic acid. Also growing human growth hormone levels via fasting and exercise techniques or using semorelin or such peptides. A lot of skin health has to do with gut health and fasting windows and reducing carbohydrates, lectins, and processed food.

[McAwesome]

Topical hyaluronic acid generally seems to be a bit overrated in its anti aging benefits. The difference compared to the plethora of other humectants, including the all too common glycerin, seems negligible. Glycerin unlike hyaluronic acid can also penetrate to the level of the dermis.

[j.du]

It plumps the skin, but lecithin will do something similar while also being excellent for internal tissues as well, and will also provide hepatic protection

[EduardQualls]

Your presentation of different methods of HLA intake are extremely valuable. I started taking it orally after I went through two series of HLA injections directly into my knees. (Yes, that sounds scary, but the MD used ultrasound imaging to make sure the needle never touched anything sensitive: the only thing I felt was a small prick on needle-insertion, then the pressure of added fluid within the knee capsule.) Those saved me from having to have knee-replacement surgery! (Before that, at one point, I was 45° leg-pressing 1100 lbs. [have never taken steroids]; probably too much.wt, tho..)

[travv]

I really like this kinda content. You're crunching through all these studies.

[fareloz]

I feel a lack of study that compares not only to some placebo in skincare, but to other humectants too. To me the reduction of wrinkles seems to be connected to hydration provided by HA. In this case I suspect any other humectant, like Glycerin/Urea/Sodium PCA, will do the same job.

[dennysevilla]

I’ve been taking hydrolyzed collagen and HA supplement for a month now my lower back pain is gone now thank you science!

[grmalinda]

Oral vitamin l vitamin E prevented my stretch Mark's from worsening after first . Had 3 more. I think it may be a kin to wrinkles in some way. Also white fish seems to prevent forehead lines and pine bark extract for between the brows. At 68 I'm not selling just sharing. 🦉

[aljosarojac]

I value a lot the fact that you compare "things" and then try to draw some logical conclusion. Great video.

[Carefulmama]

Thank you for your research. I wish you were in charge of the FDA

[presence]

I've taken HA orally in various forms and it really seems to work. Makes my face noticeably smoother & softer.

[itsokiie]

Absolutely love this video, I dont really have a deep care for skincare ( currently ) in my life, but Analysis type content & the way you show the information is phenomenal. definitely going to look for more of this on the channel & excited to see more in the future. considering sharing this information with my mother as well!

[wmichaelh]

When I noticed how often you touch your nose in various ways, it made me think of Prince Charles (now King) at the wedding of his son, William, when as he entered the Cathedral, in one sweeping movement stroked along his lengthy proboscis and continued the movement reaching out to shake the hand of one of the clergy. Thinking as I do I wondered if the clergyman wondered to himself where that nose might have been recently. Inspired by his hacked message to Camilla. Thought I'd share.

[robertdwyer]

Great channel! Thank you for the varied health focused study summaries.