Dyslipidemia - Part 4: Laboratory Parameters & Lipid-Lowering Agents

First-line lipid-lowering agents are statins because they’re generally well tolerated and can reduce total and LDL cholesterol levels by as much as 60%. Statins block the body's cholesterol synthesis by inhibiting HMG-CoA reductase. With this, they inhibit the key enzyme in cholesterol synthesis that converts HMG-CoA to mevalonate.

Outline:
00:00 - Laboratory parameters
03:15 - Blood lipid levels
07:11 - Lipid-lowering agents

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👍Common causes of secondary dyslipidemia include:
obesity, especially excess weight around the waist.

diabetes.

hypothyroidism.

alcohol use disorder, also known as alcoholism.