Histone modifications (Introduction)

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This is an introductory video on histone modifications (Introduction) and how it affects gene expression and chromatin landscape in a context-dependent manner.

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I learned more from this video than I did in my entire genetics semester. Thank you

teammatt
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Thank you, a really great video. I like the bar code comparison at the end. I think that one of the cerebral challenges to understanding histone and DNA modifications is to recognize, in the first place, why they are necessary and moreover, how they allow so so many genes to be read, written to, read again, erased, written to again, read again, etc, switching genes on or off, or modulated in some way. The mental barrier is because the focus is too close, to see the big picture. If the big picture is explained FIRST, in broad outline, reasons, and underlying principles, then the mind, when focusing on the fine detail can connect it back to the big picture. So for example, if these medications are explained from the outset as 1) allowing the base 'bar codes' of genes to be read to enable new bar codes top to be created and 2) that new bar codes to be read to do the same, then this creates in the listener's mind and expectation of where the details are heading, or where it connects. I hope that makes sense.

molecularunity
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The most comprehensible video on this topic. Thanks so much!!!

mariyamsiraj
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complete and comprehensible, perfect!

maxdebord
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I LOVE IT THANK YOU SO MUCH. YOUR EXPLANATION STYLE IS WONDERFUL.

sarasanchez
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Just so cool man! Im a chemist going into this world and for me this is jus freaking spontaniously amazing

VeganLifestile
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Thank you so much, this really helped

djtyse_za
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You are really doing great. I am referring your videos to my students. The animation is great to explain genetics. Wish you success. From Kolkata

quoeleebiswas
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Beautifully done Arpan, we need more people like you.

sahinlandman
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I searched for histone modification alot but didn't find anything interesting except this video. You went into detail and I really liked it. Please make more videos that help medical students.

azadekiani
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Very well explained thanks alot sir 🙏😇 May god bless u with lots of love and blessings

rikkigupta
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Thank you so much. I am doing a research to access the level of Histone acetylation in thyroid cancers using immunohistochemistry and image analysis. This helped me understand the basic 🤗

drnishalpaul
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Great explaination. Thank you for the video.

bindiyabajracharya
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Your explanation is the best! Thanks a lot!

oksanakoptelova
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Tqsm sir, this concept I couldn't understand in my university class but from your my concept become crystal cleard

neelu
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Hi Arpan. You are one of the best educators in this field. Your thorough presentation has helped me further understand its mechanism in conjunction with my text books. I do have question. For chromo and bromo domains, can you briefly describe their transcription and translation pathways? Thank you.

healthbabe
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Thank you so much for clear explanation

indiraprakoso
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I’m really really thankful for this…it helps a lot in short time..you are a great man..keep it man..love from pakistan ❤️

haseebgill
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I learned more from this video than I did in my entire genetics semester. Th!

davidtantz
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Congratulations for the explanation! This helped me a lot!

gustavohenriqueferreiragon