Epigenetics - An Introduction

This sketch video about epigenetics was created by Armando Hasudungan, in collaboration with Professor Susan Clark and Dr Kate Patterson at the Garvan Institute of Medical Research. It has been created for a broad, non-expert audience to highlight key messages about the role epigenetics plays in biological processes like development and diseases such as cancer.

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[NutriGamiAstrid]

Armando,
Your videos are awesome! It is not only the drawing, but also, all the knowledge
that is behind them. Congratulations!Greetings from Mexico.

[armandohasudungan]

🧠 TEST YOUR KNOWLEDGE FROM THIS LECTURE! ✅

[thanhthai]

Thank you! You are always amazing with your drawing and teaching! Please continued, some of us are visual learner.

[BobvanH]

You are a great educator! Thank you for this very good clarification.

[AnhMiT]

Thank you so much. Would you please do more videos about Epigenetics? I want to go more details about DNA and Histone Modifications. Thank you. Your videos are always great and understandable.

[Shadow-bxri]

In case of explanation, it was awesome. In such a concise mode everything was elaborated very well. 👍🏻

[martinvalenta]

Excellent video, thank you very much. I would also like to add that nowadays RNA-interference (siRNA, miRNA...) is also classified under the basic mechanisms of epigenetics. At the time when this video was created, they did not have enough information about RNAi, but it is a rather important mechanism :)

[karensenica]

Wonderful presentation, as always! Thank you so much.

[stellarlove]

If disease processes like cancer can induce altered patterns of genetic expression, it seems like it would follow that healing processes resulting from beneficial lifestyle and dietary practices (eg. turmeric, green vegetables, moderate exercise) can induce positive genetic alterations in that which is encoded and expressed.. I'm finding the term 'epigenetics' is now broadening to accommodate this notion.

[yosepsutandar]

Very useful explanation of yours. Thanks for your short lecture about introduction of epigenetics.

[lizzy]

Beautifully done! Nice refresher for me. :)

[rickyroko]

You're videos are so groundbreaking. I love you

[ehtishamulhaqmakhdoom]

Never seen such a beautiful reprisention of epigenetics

[plasmolysis]

Absolutely brilliant more especially the animation. Absolutely impeccable

[sheilakennedy]

Thank you! Great explanation, you make a complex concept manageable. Kind of like the histone complexes do with two meters of genetic material... well done.

[xoxomikimouse]

this is such a great video it helped me understand so much that reading txt books wouldn't help me. please continue making more videos on this topic please :)
thanks for your hard work!

[garr]

Does anybody knows what does he mean by "promoter region" in min 3:19? Also, is it always the case that DNA methylation leads to gene silencing and histone modification to gene activation?

[bergweg]

how do these gene expression regulators "know" in what part of the body they are located?

[saikumar]

Epigenetic research uses following molecular biologic techniques -

1.Chromatin immunoprecipitation*

2.FISH*

3.Methylation sensitive restriction enzymes*

4.DamID*

5.Bisulfite sequencing*

[sreejeshb]

Good presentation wonderful explanation!!!