T cell Activation and differentiation (FL-Immuno/31)

This video lecture explains the two signal hypothesis of T cell activation.

[harryevers]

This was brilliant. I was using the Kuby Immunology text book which I felt was just over complicating the whole process and was very unclear as to what the two signals were. This video fixed all that in 5 minutes and was short and sweet!

[jelenatj]

This 5 min lecture was more helpful than 3 hrs lecture with my professor lol

[dariav.]

Thank you a lot for your videos, I never knew immunology could be so simple

[faialnashmi]

This is more than great. Brief, informative, and crystal clear! Thank you :)

[iangte]

Whoever made this videos. Thank you . You are amazing.

[eja]

This video is really helpful, the explanation was very clear.. I Love it! 😍

[srilakshmikalidindi]

Your lectures are so precise and excellent! Thank you so much. I would have never
understood this topic without your lecturers.

[redwanrimon]

Thank you for the crystal clear concept

[camillam.]

i think the activation of CD8 t-cells most often require the help of a cd4 t-cell (which produces the IL-2 that reaches the CD8 t-cell and induces its proliferation)? its like: cd4 t-cell and cd8 t-cell are bound to antigens on one APC..
at least thats whats written in janeway immunobiology book: the CD4 T-cell stimulates the APC to increase co-stimulatory molecules like 4-1BBL and b7 and this co-stimulates at the same time the CD8 T-cell bound to the APC and leads to the activation.. and IL-2 leads to the proliferation.. or am I wrong and thats a different process?.. i am a bit confused :(

[hohnjopkins]

What software are you using to time the slide builds out with the voice over? It would really help me thank you for the videos they are awesome

[emannagy]

That was really so much helpful
thanks sooo much

[fweetnm]

Thank you very much it reallly helped mee

[michaelkhuvung]

Does CD8+ require costimulation interaction of B7 and CD28 for proliferation and differentiation?

[karisihem]

Prooving depend origin antigens or class molecules HLA ???

[mustajabalam]

Thanks....plz also upoload videos on techiques used in immunology with detail and interpretations like electrophoresis and others

[martinkullberg]

It looks like 2 acces keys to activate a deffense weapon. Is it also possible they activate per exident (by mistaken indentity (in a pathogen)/or chemicals?

[mustajabalam]

upload polymorphism and linkage disequillibrium

[mustajabalam]

Great video ....what are ur reference books for immunology plz

[toulinma]

do activated t-cells PERMANENTLY release Cytokines or just when an MHC binds to it

[leelavattikuti]

After mature naive cd4 + t cell leave the thymus and enter secondary lymphoid organs to need activation (its own self antigen presenting cell ) or pathogen