DNA & CHROMATIN | Introduction to Epigenetics

Hello everyone! Today’s video is all about DNA and chromatin, and this understanding is essential for then going on to study epigenetics (which is such an exciting field)! The time stamps are linked below as usual to help guide you through the video, and feel free to leave any questions down in the comments section down below! Enjoy 🧬

TIME STAMPS

0:00 | Introduction
0:36 | DNA and the human cell nucleus
2:04 | What is chromatin?
2:48 | Why do we have chromatin and not just naked DNA?
07:16 | The six stages of chromatin compaction
12:03 | What are nucleosomes?
17:41 | Heterochromatin and euchromatin
20:19 | Outro

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FAQ

Who are you? | I’m Holly and go by Holly Gabrielle online, making YouTube videos, running two businesses and having lots of fun
How old are you? | I’m 23
What is your academic background? | I am currently studying as a master’s student at UCL as part of their Cancer MSc programme, and before this I completed my undergraduate degree at the University of Cambridge in Biological Natural Sciences (2016-2019)

REFERENCES

Human chromosomes | Introduction to Cytogenetics, A.B.S Giersch, in Pathobiology of Human Disease, 2014
Chromatin compaction | Chromatin J.Y. Lee, T.L. Orr-Weaver, in Encyclopedia of Genetics, 2001
Cell Cycle | Google Images

[plaura]

As a french teacher of biology, I am really impress of the way you explain. Yours biology videos are so interesting.
You teach very well !
I look forward to your next videos !

[cambuletaesporreta]

I'm studying 2nd of Pharmacy in Barcelona and tomorrow I have an exam about Molecular Biology and this video was really helpful!!
I like watching scientific videos in English because I would LOVE to study in England one day😍😍 (I'm a bit obsessed with your accent hehe)

[adelakovalikova]

This video is nice summary for my epigenetics exam which I am studying for now.

[diorboateng]

I'm currently doing a project on cancer epigenetics on my internship totally love ittt 😭

[peachy]

I just graduated high school, but I am watching this for fun :D

[n.k.]

This is so interesting. I really want to study biology after graduating and this just proves to me that it is the exact right thing for me to do. Thank you! So excited for this channel.

[anniewayschas]

omg love you! could you do more stuff on inheritance? its killing me in school :( I like bio but as a fan of botany related stuff genetics is making me hate it so so much

[hassetdereje]

Thank you sooo much holly i really like your videos.

[jayashreerakshe]

HOLLYYY YOU SAVED MY VIVAAA ILYYYY😭😭😭😭😭

[kzn]

I am a MSc Medical Genomics student and I recently came across this video randomly while browsing YouTube genetic content.
I've got to say if that had been the way my teachers explained genetics in secondary school everyone in my class would have started loving biology.
Well done on the factual information and cool ways to explain!
Looking forward to more genomic content :)

[nupurkumar]

I recently studied about cells and their structure in school but it wasn't in detail bcz I'm in 9th grade. This makes it so much more interesting and I can't wait to learn more. Thank you Holly, for making biology even more fascinating for me.

[Shreya-rbem]

Tysm for another informative and interesting video holly💚💚

[luanafujishima]

Heeey Holly. I just want to say I'm absolutely LOVING your videos. I'm from Brazil, and I'm currently in college, to become a physical therapist. Not only your videos help me revise all the basics, but they really help me with my english. Great work darling, keep going 💕💕💕💕💕💕💕

[winniwinni]

perfect repetition for my cellbio exam tomorrow :)) thanks holly!!

[greenlady]

I got excited as soon as I saw your video..❤️❤️

[dhanvid]

wonderful teaching holly your biology explanation is excellent I am a 14year old student I was wondering
1.if blood cells do not genetic material then how do they multiply or replicate
2. why is it that blood cells do not have genetic material or what would happen if it had one
3.how does a cell repress or turn off a gene and by what process

[Julia-rmim]

My a-level biology finals are in about 3 weeks and i have just revised this topic. The oral exam will either be about genetics, ecology, neuro biology or behavioural biology and I hope i'll get genetics or neuro because it is way more interesting. I love this channel and your main channel as well! 😊

[amiiishaaa]

really needed this video!!! genetics stuffs are so confusing!!!

[yashaswita]

Holly!! This channel is so incredibly fresh in terms of the kind of content it brings. I really hope more people discover this channel. You put everything in such simple words that I always get so so consumed that i am surprised that I actually finished the video in one go. Great work you are doing here♥️ I love it and already cannot wait for all the content you’ll put here😁

[ZoeNelson-kn]

This video was so helpful, thank you so much!