I Took This Nootropic For 30 Days, Here's What Happened

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DISCLAIMER: This content is strictly the opinion of Dr. LeGrand and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. LeGrand nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.

[Crackerjuice]

NEWS FLASH- He's talking about DL Phenylalanine.

[THEMADPROFdj]

For those who may not mind diving one resolution layer deeper:
D [dextro-rotary] and L [levo-rotary] are stereo twins of eachother. L- and D-amino acids are two possible orientations of a particular amino acid in nature. With few exceptions [some bacterias use D aminos for building blocks] amino acids in human biology are usually the L variety.
They are the mirror image of each other.
Also, they can be considered as the isomeric forms, stereoisomers or enantiomers. while L-amino acids can rotate plane-polarized light counterclockwise in a process called levorotation, D-amino acids can rotate plane-polarized light clockwise in a process called dextrorotation. It has been considered that only L-amino acids are utilized in mammals, including humans. However, because of the recent development of sensitive and selective analytical methods for detecting chiral amino acids [125], diverse D-amino acids have been found in mammalian tissues. The physiological functions of these D-amino acids are being gradually clarified. Known exceptions are D-Serine used as a neurotransmitter that competitively docks at Glycine sites of the NMDA receptor complex, making it useful in addressing conditions such as schizophrenia, ADD, and some neuralgias. Similar activity with D-Alanine.THE D IN DLPA IS EXCLUSIVELY DERIVED SYNTHETICALLY D-Phenylalanine (DPA) is an inhibitor of the enzyme (enkephalinase-a carboxypeptidase) known to breakdown (catabolize) endorphins, especially enkephalins. Thus, if we increase brain enkephalins by administering DPA, the amount of enkephalins will increase in the brain. HOWEVER, the D form of Phenylalanine DOES NOT contribute to the L-DOPA >catecholamine pathway, only its L isomer does. It has also been demonstrated that D-amino acids, such as D-serine, D-aspartate, D-alanine, and D-cysteine, play important roles in the nervous and endocrine systems. It is VERY IMPORTANT TO NOTE that D and L forms of a chemical, DESPITE HAVING THE SAME NAME, ARE AS DIFFERENT FROM EACHOTHER AS ANY TWO CHEMICALS WITH DIFFERENT NAMES including their properties! As an example of this fact: The D form occurs commonly with many molecules you may be more familiar with such as glucose and other sugars, My favorite, Amphetamine, whose L form is Over The Counter in most countries including here in The USA. Yet whose D form may land you in a heap of trouble without proper approval or a reliable plug!

[bluegrasslady]

Great info. Music is very distracting. Thanks.

[chrissmith]

The peer reviewed studies I found do claim to have found positive outcomes in the use of DL-Phenylalanine for ADHD compared to placebo. However, it would appear that the effects of the drug wore off after 3 months.

[dawnkulan]

This is crazy 🤯 This is EXACTLY what I used to take every day, especially workdays, BEFORE I knew I had ADHD. I don’t even remember where I read about it but I do my research which is how I just found you on YouTube. 😉 Btw, I was diagnosed less than 2 years ago at age 45. I still can’t focus. I’m going to purchase and start taking again. And I do take ADHD meds. Thank you!

[AlexanderNilsson]

Man, I really appreciate what you're doing!

[safirijorgensen]

What company do you use for neurotransmitter testing?

[stuartsherman]

Can I get more information on how to get tested on what my brain is lacking like you did before you took the dl-phenylanine? I totally agree, prescribing adhd drugs without testing is just guessing.

[BenThrockorton]

Interesting. I lived with my ADHD for most of my life. I was not medicated, but I noticed that in my mid 50's it was starting to affect my job. I finally mentioned it to my doctor and he started me on adderal. I would like to do something more natural if possible. I am just curions where to start.

[patriciaoflynn]

This is really interesting, thank you so much for sharing. I have dyslexia and as I have been under a lot of stress in the last year I feel my executive functioning, mood and focus have been getting worse. How did you get the urine test at the beginning of the video? Some sites say that testing for neurotransmitters is inaccurate. It it more that you are testing for the protein precursors?

[TCSCskater]

I love DLPA. Very helpful for stimulant addiction and other dopamine issues as well as opiates.

[IreneBrown-mb]

I'm interested in learning more about nootropic supplements, including whether normotim is a worthwhile choice.

[DanaCurtis-]

Have you tried nootropics from normotim? I would like to see a similar video about other supplements

[fatihainulyaqin]

You so genius to relating your content

[imnutrak]

The peer-reviewed studies I found suggest that DL-Phenylalanine has positive effects on ADHD compared to a placebo, though these effects seem to wear off after three months. However, three months is a significant period to establish habits, and transitioning off the supplement while maintaining those habits through dietary sources like eggs, dairy, meat, and soy products could help sustain the benefits.

[steveamini]

Hi doc
Did you check your PEA after using Dl phenylalanine!
I have abeen Using DLPA for 5 yrs
I get same benefits like yrs !
But I still don't know if is increasing PEA or not !
PLEASE Let us know if you check yr PEA
Thx

[Mythron-ln]

Dear Dr. LeGrand,

Despite taking Methylphenidate Hydrochloride and Lisdexamfetamine, I have not yet achieved an ideal state of concentration, focus, and overall well-being.

Therefore, I would like to sincerely thank you – especially for your extremely informative and, from my perspective, medically valuable videos on L-Theanine and Phenylalanine. They have provided me with new and insightful perspectives.

In this context, I have an important question:
Is it possible to take L-Theanine and Phenylalanine together?
If so, would it be better to take them at different times of the day, or is it generally safe to take both together in the morning?

Thank you very much in advance for your time and your valuable work.
Kind regards from Hamburg,
Dennis

[dbinvr]

I’m going to get the neurotransmitter urine test asap, I did not even know that was a thing!!!

[faitht]

My son was diagnosed with ADHD and he's on three medications (ADHD, anxiety/depression). We haven't seen any improvement over the past three years. Thanks for your educational videos.

[skinflint]

Great info as always! Did you test again, to see if the values improved?