How to Treat Alzheimer's & Parkinson's Diseases | Dr. Mark D'Esposito & Dr. Andrew Huberman

Dr. Mark D'Esposito and Dr. Andrew Huberman discuss the complexities and challenges involved in understanding and treating Alzheimer's disease.

Mark D'Esposito, M.D., is a neurologist and professor of neuroscience and psychology at the University of California, Berkeley. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab podcast.

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[dianacolvin]

My mom has dementia. She was diagnosed 3 years ago. I’ve noticed on the days I give her high quality fish oil, low carb/high fat foods, and plenty of spring water, her moods are so much more stable and she seems to be more clear.
Also, for short term memory, she only remembers the things that evoked an emotional response. Daily mundane things she forgets. But anything that made her really happy she seems to remember… like our outings together 💖💖💖i pray a cure is found- SOON. I don’t want to lose her.

[healing]

It's heartbreaking to see anyone go through these diseases. We had to care for multiple family members with dementia under the same roof at the same time as well as having others go through it at the same. I was thinking it at some point that it was genetics - at least 10 cousins of the same age in different countries all had it. I made a family tree and added everyone's cause of death that we could, we looked at their descendants - IT'S SCARY. I saw mainly inherited lifestyle choices as the main issue. Common issues - dehydration, barely drinking water, living on coffee, some were chain smokers, some drank wine with every meal, a lot of pork in their diet, they all had dental issues - amalgam fillings, root canals, tooth loss, otherwise they were all very active people, social and ate a whole food diet. I was beside myself on how to balance things out, they all went down hill when they were put on medication. It was a living nightmare, family members couldn't handle seeing the rest of them like that all together.

[enterprisar]

I think Hubermann needs to have Dr. Ali Rezai from the University of West Virginia Alzheimer’s Clinic on the show and their breakthrough with ultrasound

[brilliant]

My father was diagnosed of Alzheimer's disease recently. I know there is no cure, but I understand that exercise is still the best form of treatment for the symptoms and should be the main focus before meds. He's on the meds, so let's put that aside. So for exercise my doctor warned me that if he gets too strong he could hurt people as his confusion increases. So the advice was only walking. I'd love any feedback on this, thank you

[newday]

Alzheimer’s is I believe one of the saddest diseases for patients, fiends and families. It amazes me the amount of money raised for it, and no advances truly have been made. I used to run a Memory Program in a skilled facility, music definitely was very beneficial. But it’s very sad because most affected by this disease are very healthy in rest of body. So it’s a very slow process and so hard to watch.
It was mandatory in training, for workers to watch the Terra Nova Film … Grace …the Alzheimer’s documentary, it’s is true story of the progression of her disease from first diagnosis, until her death.
It will bring tears to all eyes.

[bobgug]

No mention of Dale Bredesen who claims some Alzheimer's cases can be cured. And we know that higher VO2max correlates with slower progression of all neurodegenerative conditions. Would be worth mentioning here because it's something people can actually do themselves.

[dija]

Being that this podcast was just posted 7 months ago, I am surprised that you both did not discuss Dr Dale Bredesen and his amazing and effective protocol. My family member has been on it now 2.5 months and is already showing signs of stabilization and even small signs of recovery. It is a very hard lifestyle change for someone who is not used to Keto style eating, weigh bearing cardio exercise.. but to his credit he is doing it! We are so proud of him. We are helpful to him and very hopeful that as the months and years go by that if we can at least stabilize him where he is at, we will be so happy because he is in AD's early stages.

[DrSnowBrainHealth]

Percepta is a major breakthrough actually… we have data this works on severe memory loss in patients…the data will be out in the next 6 months

[Doe-Nutz]

RIP My Father who has Died from ALZ.
It was Tough to See him go through All of miss him very much❤️💯💎

[marcanderson]

Why the misleading title? "How to treat..."

[marinac]

9:41
What about protective measures/strategies regarding Alzheimer...speaking many languages?...does it matter at what age one learns a new language or can it be done at any stage ? My understanding was - it has to do with neuroplasticity/ establishing new /additional neural connections which one can "fall back on" when others get affected/"destroyed" by Alzheimers etc

[HollyF]

High dose niacin therapy (nicotinic acid) can also activate the nicotine receptors in our body to produce the same effects.

[DrSnowBrainHealth]

Might want me a guest on your show…fastest growing brain health channel…DrSnowBrainHealth…I worked 35 years on Alzheimer’s since i was 20 years old…

[JamesHouk-um]

What about SS-31 and mots-c to heal the mitochondrial function and prevent cytokine production?

[maramkraida]

I just have one hope in dealing with Alzheimer and I guess it is antibody Therapy as well as modulating drugs. We need more doing autopsies to get much more Information about the physiological changes and the cell turn over of the astrocytes. By the way I don't believe in that social activity and social engagement a protector factor! I had two family members who suffered from it and both were very social beings.

[thomascenteni]

I'm 31 and have early signs of Parkinsons. I have difficulty getting on my left side when I walk and I Have constipation too. How can I stop it from getting worse? My neurologist doesn't think I have it but he's pretty careless

[DrSnowBrainHealth]

You might want to have a real Alzheimer’s pioneer on your show…The Unifying Hypothesis of Alzheimer’s Disease by Dr Alan Snow as hypothesized 30 years ago …heparan sulfate proteoglycans are key …

[destroy-erase-improve]

Major improves to my 81 year old father going onto a carnivore diet.

[thepranayamamama]

Thank you both for helping us better understand what is going on with our precious loved ones.. your efforts are massively appreciated 🙏🏽♥️🙏🏽 This is a heartbreaking process for so many innocent people and we trust that more solutions will eventually arise..💔♥️ Very important for caregivers to do whatever they need to do to stay strong and healthy throughout this intense journey.. ♥️

And you’re so right, Andrew, music is everything for dementia/alzheimers patients.. I firmly believe it’s one of the strongest medicines on this planet!! ♥️♥️♥️

Very interesting information on nicotine as well! Thank you, again!

[dannymeske]

They will never be able to reverse damage already done with Alzheimer's I'm a care giver for my wife of 42yrs. She has been sick with the disease for 8 yrs now and she know longer can carry on a conversation that makes sense, lies constantly, repeats/gets irritated, can't stay in the present moment. and she wanders and loses things or constantly wants to go home ...etc, etc, etc. she is like the Energizer Bunny with no brain. Alzheimer's is a life style disease and Americans are fat and you have to be rich to afford daily care when your brain starts to decline....I'm 78 no family to help care for my wife, the whole Alzheimers thing and what comes with it is killing me too.