What Happens When Patients Stop Wegovy/Ozempic?

In this video, Ania Jastreboff, MD, PhD, a professor at Yale School of Medicine and director of weight management and obesity prevention at Yale Stress Center in New Haven, Connecticut, discusses what to expect when stopping obesity medications like semaglutide (Wegovy).

[lynerochon]

I stopped ozempic because it caused exhaustion.

[ashannaredwolf]

You do understand that many people are taking this for diabetes and insulin resistance associated with PCOS, right?

[TheEasyDoc]

TLDR: Stopping obesity medication can lead to weight gain as the body's defended fat mass set point goes back up, causing cravings and the need for continued medication to maintain weight reduction.

00:00 📉 Stopping obesity medication leads to weight gain due to it being a chronic disease.
00:38 🧠 Neurometabolic disease involves communication between the body and brain, with the body adapting intelligently.
00:49 📉 Our body wants to maintain a certain amount of fat as fuel, known as defended fat mass set point, in our obesogenic environment with highly processed foods.
01:31 😴 Lack of sleep.
01:34 👩‍⚕ When patients stop taking anti-obesity medication, their defended fat mass set point goes back up, causing weight regain and cravings, so the medication needs to be continued to maintain weight reduction.

[ac]

Not talking about changing lifestyle at all?

[simonesobel]

I think this is such bullshit. Lots of people have an extremely hard losing weight, but not maintaining it. To maintain you have to simply get on a healthy eating program, know how many calories your body does for maintenance and stick to it. Your hunger will increase, but it's a lot easier to have a little hunger but fill your body with nutrition, then to starve yourself to keep losing weight. Hunger is normal, but someone trying to get weight off for years and can't start gaining weight die to stress levels, low self esteem and emotional eating. Maintenance is completely do able . Adding some intermittent fasting ( 12 to 16 hours) will help a lot with maintenance.