IVF - Why Embryos DON'T STICK to Uterus After EMBRYO TRANSFER ? - Dr. Sneha Shetty | Doctors' Circle

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Dr. Sneha Shetty | Phone 📞 : [phone] & [phone] (Online & in-person appointment can be booked online or by call) Clinical Director, Chief IVF Consultant, Gynaecologist and Laparoscopic Surgeon | Vriksh Fertility, HSR Layout, Bengaluru, India | Registration No. 96567 Karnataka Medical Council, 2012
So usually after an embryo transfer, if it is not successful, we again go back and check whether your stimulation has gone properly or not. How the quality of the eggs were, how were your embryos and should we change the stimulation in order to make certain equality better, can we do something in order to change the outcome for it for the next embryo transfer or for your next IVF cycle. So what could be the cause why your embryo did not stick to your uterus? Number one could be a problem in your uterus itself like if there is any kind of infection in your uterus be it tuberculosis or any other infections. We have to rule out that number two in the uterus itself could be abnormal uterine shapes like how we have a septum in between in our nose, the same way we have certain septum in the uterus also for certain people, which we call as uterine septum. If in case something like that is there we may have to go through vagina inside your uterus through a procedure called hysteroscopy and remove that septum. That is called Septal Resection. So that we have to check. Sometimes some people are born with abnormal uteruses like they have two uteruses or they have two horns of the uterus or they have a uterus which is bent towards one side like this. We have different abnormalities in the uterus as well so we have to check whether there is something like that and rule out that condition also. Also we have to rule out certain immunological conditions wherein your body itself rejects the pregnancy or the embryo thinking that it is a foreign object which is entering your body. So in certain conditions like that we have to do further testing to rule out immunological causes prior to the next Embryo transfer or the next IVF cycle. Apart from this we have to check whether the egg quality was good or not whether the embryo quality was good or not how was the sperm we may need to assess the sperm as well and do additional testing like DNA fragmentation test. So in DNA fragmentation test what we do is we check whether they are DNA damaged sperms, how many percentage of them are there in the entire semen sample. Normally because of all these lifestyle factors, pollution, pesticides and all this generally all the men who tend to have 10 to 15 percent of the entire semen sample will have this DNA damage sperms. If it is more than that then the chances of that sperm being injected into the egg or doing IVF with it will be on the higher end. So such embryos usually they'll have some DNA problem and they do not implant or even if they implant they tend to cause miscarriages. So we have to rule out that. The DFI is not very high. So sperm testing also is important you can do that. So along with that you also have to rule out whether there are any genetic chromosomal problems which are present in the embryo. So genetic problem if it is present in the embryo even such embryos will not usually imply or even if it implants will not continue to be a healthy pregnancy. So in such conditions we advise to undergo a test called Pre Genetic Implantation Testing PGT a testing which will rule out any kind of aneuploides which are present in the embryo which is nothing but genetic abnormalities like Down Syndrome etc which are ruled out before placing the embryo into the uterus of the female partner.

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[pavithrab]

Thanks Doctor. I’m waiting for my ET, doctor wanted to rule out tuberculosis and I’m in process of it. Had a question in mind as “Why” and this video helped.

[srividyaathmaram]

My bladder can't be seen..so they gave saline water in bladder.Is it common..pls some one reply for this

[jayadama]

Dr.Shetty no.4 how to make in your embryos?

[nupurnb]

Grade 1 embryos also need to do pgt testing?

[MelissaStrickland-xftk]

Sure enough, if everything goes well this should do the job. But listen, there's one factor that's usually overlooked that can considerably speed up the process, unfortunately I do not have it at hand, but it can be go’ogled Dobbie Nerkstrol's Infertility Cure, I think.

[sindhulavithayyappa]

Mam my 1st cycle becomes positive, but no heart beat in 8th week, so doctor said said it is missed abortion, it happens in june, im working women, n my age 37, n I get leave after October, it almost 5 months gap from 1st cycle, is there any problem in this much of gap? Can i start 2nd cycle after October, plz suggest me mam,