Microdosing: Fact or Fiction? - UC Davis Psychedelic Summit 2023

The UC Davis Psychedelic Summit brought together national experts to explore what the rapidly evolving field of psychedelics and neurotherapeutics may mean for neuropsychiatric and neurodegenerative diseases. These new treatment types may hold promise for anxiety, depression, substance use, obsessive-compulsive and post-traumatic stress disorders, among others. The event was hosted by the UC Davis Department of Psychiatry and Behavioral Sciences, the UC Davis Institute for Psychedelics and Neurotherapeutics, and the UC Davis Behavioral Health Center for Excellence.

0:00 Introduction
0:26 Psychedelic drugs and depression
2:29 Microdosing LSD explained
9:14 LSD in animal models
10:18 Human studies with low doses of LSD
17:02 Study 1 - Behavioral dose determination
24:26 Study 2 - Effect of LSD on functional connectivity fMRI
25:23 Study 3 - Effects on EEG
28:39 Study 4 - Repeated microcode study
36:13 Latest study - LSD in participants with high vs. low depression scores
38:48 Remaining questions after studies
41:40 Questions from the audience

The information in this video was accurate as of the upload date, 5/11/23. For information purposes only. Consult your local medical authority for advice.

#microdosing #psychedelics #lsd #ucdavis

[AndrewParker-ssli]

Psychedelics definitely have the potential to deal with mental health issues like anxiety and depression, they really helped me.

[brooklynbaywatch]

I have been depressed for a long time, but after taking shrooms few months ago, l feel much happier and highly motivated and my ADHD gone, lost a ton of anxiousness and had a few epiphanies about how I should live my life. I decided to buy an ounce for backup, but haven’t yet felt the need to take any more since then.

[ngunhmung]

Several types of research has proven psychedelics as a beneficial substance in terms
Of medical use.

[Kristenjenner-xsdr]

Psychedelic mushrooms really helped years back. Totally got rid of deep depression, anxiety and brain fog. Microdosing is truly beneficiaI.

[Lemonz]

It had a tremendous effect on my chronic migraines, and I've heard people take it for cluster headaches too. I don't think it's placebo in my case, because I've taken so many medications expecting them to work, and almost nothing happened. This worked almost immediately. After two days my "background headaches" almost vanished and I haven't had a migraine for almost two weeks now, which is extremely rare for me.

[tapeweight]

I’m 47 years old . And life has been ruff 🐶 emotionally. I micro dose every now and then . And it motivates me to do things . Takes muscle pain away . And just makes me happy happy happy. It’s insane to me in how long it takes to get a great thing into the general population. But we can get all other kinds of pills 💊into the general public that kill people everyday . Grind some up put a teaspoon into some tea ☕️ or coffee or water . And enjoy 😉

[officialkimberly]

Research has shown psilocybin to have potent to treat a range of psychiatric and behavioral disorders.

[Keeplerb]

yey:) Ive been tripping my whole life. First time I was jsut 14 years old (im 53 now). I ate 250 raw magic mushrooms. That trip is imprinted upon my soul. My brain developed on psylocibin. I microdose when Im very busy or doing some creative work. Work like wonders everytime :D Especially with my bass playing. If your locked up in some bad training patterns you pop right out of it when microdosing and you suddenly sit there with a cool riff. But if youre going to do a proper research of your subconsciousness I recommend a high dose. Thats the only way to have a vivid dialog with your subconsciousness and to do some real healing and face your demons if you have some (for real). Please dont correct my grammar.

[TheBayAreaBackyardsBee]

Thank you for the information and research work your doing. You are all greatly appreciated

[vladislavyakushin]

Such a good study. I think it deserves much more views

[ashleymasoner]

Mother nature will always be more powerful than us humans. We’ll never be able to scientifically categorize and figure out this beautiful gift on earth from the gods. You can muck it up all you want with science, taking the spirituality and creativity out of it, which seriously pisses off the spirits, but it will never be what it was made for with scientists trying to “figure it out” for all. Aboriginals know this best. I do agree that dosing should be talked about and experiences shared. All we have to do is legalize it to get there. Stigma created by what the government has done to this absolutely wonderful medicine can only be broken by transparency in conversation, bonding, support, encouragement and love. In my opinion it is a disservice to people seeking healing to try to figure this out scientifically and then make promises and suggestions based on that. Powerful brain portal substances enter the hero that takes them and do the healing alongside a willing, submissive and respectful user.

[lizcruz]

Been reading through the EEG paper mentioned for my job. Amazing work!

[Roycutsnfishes]

I’ve been on Paxil 20mgs for 3 months at about the 2nd month I noticed I couldn’t get as stoned anymore so I started smoking stronger bud and barely anything, then I shroomed .5 then 1.5 chocolate shrooms fyi and different days then I got penis envy ate 2gs and NOTHING either, I’ve tripped before already but the meds are keeping it from taking effect…so I’ve been weaning off the Paxil so I can start microdosing, I’d rather mushrooms

[THERAGINGPOTHEAD]

It's not a drug it's a portal

[mswan]

The presenter’s dismay at having to deal with human emotion instead of rodent head-twitching in her research is pretty funny.

[susannar]

I like to check all kinds of studies and what is the dicussion in the field. Where pharmaceutic-studies fail, is same as in here; they are treating psychedelics same as "man-made drugs". For example, whes she says things like "no drug can effect multiple things" (well, you can heal multiple problems with good diet, not just one), and other things... medicinal field is not going to be the right field for studiyng this, because their styles of studies doesn't fit for this properly, and they dont understand that this cannot be compared to western medications.

[ern]

My theory is that that most people that experience legitimate benefits are the ones going closer to the threshold of getting high.

[StrangeSituation]

Is she saying psychedelics can cause blindness?

[noelalam]

there are holes in this study. they never measured the subjects tyrosine, tryptophan, and other vit, minerals and amino acid levels. no matter how much psychedelics you take without the proper nutrition you will not gain the benefits in the long term.

[gratefulkm]

To FEEL the affect of an Anti inflammatory you must of course be inflamed in the first place
otherwise known as
"its easier for a camel to walk through the eye of a needle than it is for a rich man to walk through the gates of heaven"