Meningeal Lymphatics In Brain's Health and Disease - Jonathan Kipnis, PhD - LE&RN Symposium

Meningeal Lymphatics In Brain's Health and Disease - Jonathan Kipnis, PhD - LE&RN Symposium

Jonathan Kipnis, Ph.D.
Harrison Distinguished Professor and Chair, Department of Neuroscience
Director, Center for Brain Immunology and Glia (BIG)

Dr. Jonathan (Jony) Kipnis’s research group focuses on the complex interactions between the immune system and the central nervous system. The goal is to elucidate the cellular and molecular mechanisms of these interactions in neurodegenerative, neurodevelopmental, and mental disorders as well as in physiology (including healthy aging).

Dr. Kipnis’s research team showed that the brain function is dependent, in part, on the function and integrity of the immune system and that immune molecules (cytokines) can play a neuromodulatory role. The fascination with immunity and its role in healthy and diseased brain is what brought the team to a breakthrough discovery of lymphatic vessels that drain the CNS into the peripheral lymph nodes and thus serve as a physical connection between the brain and the immune system. The implications of this work are broad and range from Autism to Alzheimer’s disease through neuroinflammatory conditions, such as Multiple Sclerosis.

Dr. Kipnis graduated from the Weizmann Institute of Science in Israel, where he was a Sir Charles Clore scholar and a recipient of distinguished prize for scientific achievements awarded by the Israeli Parliament, The Knesset.
Dr. Kipnis joined UVA faculty in 2007. He is now a Harrison Distinguished Professor and Chair of the Neuroscience. Since 2015 he is also a Gutenberg Research College Fellow at the Johannes Gutenberg University Mainz Medical Center, Germany. In 2018 he received a prestigious NIH Director’s Pioneer’s award to explore in more depth neuro-immune interactions in healthy and diseased brain.

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Our Mission is to fight lymphatic disease and lymphedema through education, research and advocacy.
We seek to accelerate the prevention, treatment and cure of the disease while bringing patients and medical professionals together to address the unmet needs surrounding lymphatic disorders.

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[yingyingliu]

This is SUPER cool!!! I'm actually reading the papers from their lab these days, and found this amazing presentation!

[HEEEERESxFREDDY]

Great presentation! This is exciting stuff!

[ahmetsemihtopbas]

Thank you. Amazing presentation, easy to follow and very thoroughly explained.

[unparked]

What type of scans were used to see the various brains please?

[brickdorsi]

Continue to spread the knowledge! Don’t stop when met by resistance! Your a gangsta

[post-opmassage]

Do the capillary walls in the brain also have the inner lining -endothelial glycocalyx?