Conserved meningeal lymphatic drainage circuits in mice and humans

Video summary by Laurent Jacob and Stéphanie Lenck (Paris Brain Institute)

This study characterizes the 3D-anatomy of meningeal lymphatic vasculature and associated cerebral spinal fluid drainage by postmortem light-sheet imaging in mice and by real-time magnetic resonance imaging in humans, demonstrating conserved lymphatic circuitries in contact with dural venous sinuses.

Keywords: meningeal lymphatic vessels, cerebrospinal fluid, glymphatic system, light sheet fluorescence microscopy, magnetic resonance imaging, Gorham-Stout Disease