Look in the labs | Electron Microscopy Suite

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Mapping the brain is a gigantic undertaking. See how researchers at the Allen Institute are using electron microscopy to map intricate connections between brain cells at ultra-high resolution. In this lab, researchers stain tissue samples with heavy metals, embed them in resin, cut the samples into ultra-thin slices, and image them with transmission electron microscopes. Data is produced at 4nm/pixel processed by computational scientists on the team who aligns, segments, and processes the connectomics data for analysis.

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This is great work! The methods used here provide the resolution needed to actually understand how the brain works. Also, thanks for not wearing a mask in the video, it makes a big difference. I would like to see a video showing how to look at the data from the 200 spatially distributed matches from two-photon data. Do you actually have 200 segmented cells that show the exact firing patterns based on the exact cell structure? This would obviously be good truth data for everyone to use to build and verify models.

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I hope they will be able to create a complete neural conectome map of the whole mouse brain.
The collection of neural circuit data, along with the classification of brain cell types, will pave the way for elucidating the working principles of the brain.
If we can figure out how it works, we can contribute to the creation of Artificial General Intelligence.

Only Google, Allen Institute, and Argonne National Lab can accomplish that task.
Since it is necessary not only to simulate cranial nerves but also to elucidate the theory of operation, cooperation from MIT CBMM and DeepMind is necessary.
Japan's WBAI and EPFL are also requesting cooperation.

alph