Bubonic Plague still persists in isolated pockets globally!

The bubonic plague, once a devastating scourge that claimed millions of lives, still persists in isolated pockets globally but is now easily treatable with modern antibiotics. Recent cases, such as a man in Oregon contracting the disease from his pet cat, highlight its lingering presence, particularly in wild animals like squirrels and prairie dogs in the US. Despite its rarity, the plague has left a lasting impact on human genetics, evidenced by DNA findings in ancient skeletons. Studies suggest that genetic variants, like those related to the human leukocyte antigen (HLA) system, may have provided survival advantages during plague outbreaks, shaping modern immune responses. Ongoing research sheds light on its evolution and informs contemporary efforts in vaccine and drug development.
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