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Activation of a G protein coupled receptor at the cell membrane

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This short animation shows the activation process of a G protein-coupled receptor (Class B).
G protein-coupled receptors (shown in blue) can be activated by endogenous peptides (shown in green), which is followed by conformational changes in the receptor and engagement of a G protein heterotrimer. After conformational changes and nucleotide exchange at the Gαs protein, the G protein heterotrimer disengages from the receptor and is ready for further cell signalling.
Animation was produced in Blender 3D.
Music: produced in Garage Band.
G protein-coupled receptors (shown in blue) can be activated by endogenous peptides (shown in green), which is followed by conformational changes in the receptor and engagement of a G protein heterotrimer. After conformational changes and nucleotide exchange at the Gαs protein, the G protein heterotrimer disengages from the receptor and is ready for further cell signalling.
Animation was produced in Blender 3D.
Music: produced in Garage Band.
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