Activation of a G protein coupled receptor at the cell membrane

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This short animation shows the activation process of a G protein-coupled receptor (Class B).
G protein-coupled receptors (shown in blue) can be activated by endogenous peptides (shown in green), which is followed by conformational changes in the receptor and engagement of a G protein heterotrimer. After conformational changes and nucleotide exchange at the Gαs protein, the G protein heterotrimer disengages from the receptor and is ready for further cell signalling.

Animation was produced in Blender 3D.
Music: produced in Garage Band.
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Dude come back and do all your videos on YouTube shorts, just with some text, you'll be a great hit! And medical students will appreciate it so much!

morgan
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Now I know this very useful in life piece of information about how a G protein coupled receptor activates.

Catversionofcat
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Thanks for this illuminating animation! So useful for teaching.

samuelhoare
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I have a question. I’m not sure if this applies to all G protein-coupled receptors, but I saw a different animation showing the heterotrimer bound when the ligand was absent.

professorchimp
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Do membrane proteins around keratin in human's stratum corneum get thicker or swollen?

kukukukijochu
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Williams Kimberly Martin George Rodriguez Jose

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