015 - Why the microglia have turned against you

Pathogens, environmental exposures, medications, and your physical and mental states are all potential sensitizers of microglia. In this video, I cover the most likely triggers of chronic brain inflammation. - Jarred Younger

[fionaclark]

Thanks for this Jarred, and good luck with the grant. Every morsel of hope keeps us going with unrelenting CRPS and fibromyalgia pain. My beautiful daughter was five years bedridden yesterday, with the knock-on effect of her moderate to severe ME/CFS of 25 years then becoming severe for 5 years. Every ray of☀️gives us hope through the 🌧️of despair🌈and helps us to forget our traumatic history (+ black mould and bacterial + viral exposure)
We really appreciate how hard you are working to find answers❤

[AlbaLynxQueen]

I was a "double hit". I had a nasty cold that lasted three weeks back in 2021. Not having fully recovered I went to get my Covid jab. The next morning I woke up completely sick and never recovered from that flu like state. 3 years later I still have fevers, devastating fatigue, nausea, brain fog, muscle pain, etc

[Shelleysnail]

Thank you very much. Extremely interesting and informative and well enough explained to keep even those of us with brain fog in the loop.

[ProfessorBeautiful]

I'll be watching for reports on genetics and on dextro-LDN with great anticipation.
These videos are tremendously helpful.
I'm grateful you don't waste time on "production values" BS like background music, stock footage. Clear honest science is better than nonsense.

[ivorybow]

I was diagnosed with fibromyalgia in 1988. I suffered horribly and actually did kidney damage from taking too much ibuprofen. 10 months ago I became carnivore. in those months, the inflammation has calmed dramatically to the point where I rarely experience anything resembling fibromyalgia. I have noticed that some carbohydrates experience a sudden serve inflammation in my symptoms that are like the flu. Getting off of carbohydrates has worked wonders for me.

[TLDnoR]

You’re a f*cking saint for making these videos Sir

[headbangingidiot]

Babe wake up, Dr. Younger dropped a new video

[matthewmccarty]

You should make some videos on the role of the mitochondria in all of this, and how microglia / neuroinflammation affect metabolism and cellular energy production downstream!

[healMECFS]

8 years ago: EBV infection + Concussion just short time after + mold -> First Symptoms started.

7 years ago: new viral infection + high exposure to chemicals at the same time -> big Crash, since then fully bedridden.

[kathleenvaillancourt]

I am looking forward to your video on potential treatments for the microglia.

[cchawk]

I feel very fortunate to have had your channel show up in my feed!

[carrierobinson]

How sad that researchers can't collaborate more than they do. The fight for grants and the need to protect research from those that steal it and the desire to get credit means the patients endure suffering longer.

[slomo]

3 masseurs touched my muscles and said they felt abnormal. One of them said my muscles were stiff and they felt like I was wearing full body armor. So it's not just my brain misinterpreting the signals from my body. There is indeed something wrong in my body that can be felt by other people.

[Laroc]

Regarding the environment, I’d be curious about your position on air fresheners (plug in, aerosols, candles, incense, etc.), and perfumes and colognes. Particularly in poorly ventilated places. I feel this is an under addressed health hazard, and hearing you explain this makes it all make sense.

[olivertruswell]

Appreciate everything you're doing! This might be the first concise and clear explanation of a disease hypothesis out there. I had EBV and then lived in a home with huge amounts of toxic mold. I also started a business right at this time and had never been more stressed. This would make a lot of sense why my microglia could be primed.

[angelbryan]

I got my symptoms from the HPV vaccine. Same symptoms as ME/CFS and Post Viral Fatigue; Brain fog, blurred vision, anxiety and panic attacks, fatigue, fasciculations, palpitations, shortness of breath, joint pain, food malabsorption and I am sure I am forgetting more.

I soon realized that the symptoms are very similar to those of Long Covid and now it makes sense.

I am convinced all those conditions are the same disease which is triggered by a strong immune response. The question now is if recovery is possible and if so how can I achieve it.

[EminenceIncorperated]

I feel a bit bad for my microglia now because it sounds like they've just been traumatized 😄

[Laroc]

A typical day for me: drive to work and get exposed to diesel fumes and other exhausts, arrive to work and am subjected to air fresheners, perfumes and colognes, and a sick coworker, leave work and get another dose of diesel and exhaust, then arrive home. No wonder I am TIRED all the time! My body has been in a battle!

[rheabullock]

I've had two brain surgeries, first one in 2001. I basically never got back to my pre-surgical physical shape and was diagnosed with FM in 2006. My second brain surgery was in 2013. I've lost track of the number of MRI's I've had since 2001. My last one mentioned gliosis. I daily feel as though I'm awakening from anesthesia with some nausea and dizzy/woozy all day long. I've had CRP, cytokines tested with "normal" results. Long term opioid use, currently on tramadol for 18 months. Also gabapentin, venlafaxine. So tired of being tired. Thank you Dr Younger for all you do.

[Ohearty]

Wow! That explain exactly what must have happened to me 13 years ago where I had a severe infection which spread to the brain. I never got really well afterwards and suffer from a lot of chronic pain now. Never had pain before I got ill. Thank you for sharing this. It gives me hope for finding a way to help my brain finding a way to calm down again some day.