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CD33 and Alzheimer's Disease
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Previous genome-wide association studies identified CD33 as a Alzheimer's disease risk gene. Through examination of human samples and mouse models of Alzheimer's disease, Griciuc et al. uncover a novel pathway linking CD33 to clearance of brain amyloid by microglial cells. For more information, see Gruciuc et al., Neuron 78(4).
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