CBD Reduces Airway Inflammation and Fibrosis in Asthma

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“Asthma is characterized by chronic lung inflammation and airway hyperresponsiveness. Asthma remains a major public health problem and, at present, there are no effective interventions capable of reversing airway remodelling.

Cannabidiol (CBD) is known to exert immunomodulatory effects through the activation CB1 and CB2 receptors located in the central nervous system and immune cells, respectively. This study was designed to evaluate the effects of cannabidiol in this scenario.

CBD treatment, regardless of dosage, decreased airway hyperresponsiveness. There was a significant and inverse correlation between CB1 levels and lung function in asthmatic patients. CBD treatment decreased the inflammatory and remodelling processes in the model of allergic asthma.”

Research via University of Rio de Janeiro, Brazil.
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