Clinical Cuts: Diabetes mellitus

Access to affordable healthcare for folks with diabetes has been a pressing issue in many communities. But how exactly does diabetes affect the body? Today's Clinical Cut is all about diabetes mellitus.

In diabetes mellitus, your body has trouble moving glucose, which is a type of sugar, from your blood into your cells.

This leads to high levels of glucose in your blood and not enough of it in your cells, and remember that your cells need glucose as a source of energy, so not letting the glucose enter means that the cells starve for energy despite having glucose right on their doorstep.

In general, the body controls how much glucose is in the blood relative to how much gets into the cells with two hormones: insulin and glucagon.

Insulin is used to reduce blood glucose levels, and glucagon is used to increase blood glucose levels. Both of these hormones are produced by clusters of cells in the pancreas called islets of Langerhans. Insulin is secreted by beta cells in the center of the islets, and glucagon is secreted by alpha cells in the periphery of the islets.

There are two types of diabetes - Type 1 and Type 2, and the main difference between them is the underlying mechanism that causes the blood glucose levels to rise.

Diabetes mellitus is diagnosed when the blood glucose levels get too high, and this is seen among 10% of the world population. About 10% of people with diabetes have Type 1, and the remaining 90% of people with diabetes have Type 2.

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[corbinbanks]

Can't believe you guys summarized diabetes this effectively in 60secs!

[aryamangoel]

I hope you guys know how much med students respect you.

[binoymathew]

These small animation clips are a blessing to most in the healthcare community. 🤓👍

[janizky]

As a visual learner. I learned a lot from you. Thank you

[someonegg]

Wow ! It is really demonstrated in a good way, keep up Osmosis.

[eat.yourveggies]

This is so cool! Now I know better about what’s going on with my blood sugar levels, lol.
My grandpa has type 2 diabetes and so it genetically passed on to my mom, but she just had the gene. Now I have type 1

[uchithasiva]

Your videos have saved my grades thank you very much!!

[aniruddhaponkshe]

Thank you guys..your videos help us a lot!!!!❤❤❤

[MichaelCouvillion]

This explanation is faulty. The body regulates global glucose uptake using insulin, but individual cells regulate how much glucose they take in by increasing or decreasing the number of insulin receptors they express. Cells aren't starving for energy when they down-regulate insulin receptors - they already have too much glucose and any more would cause them damage. Forcing them to accept more to lower blood glucose just forces them to accept that damage. Overall glucose intake should be reduced instead.

[jha-aircraft]

Vídeo prático e objetivo facilmente de entender ...o tal mecanismo mellitus

[abdelrahmanali]

Great one question from where you get this pics, which Websites and which program do you use for editing to like these videos thank you ❤

[alfazaster]

Awesome one ❤️... keep up the good work up 🙏

[meghoughton]

So somehow the excess sugar in the blood doesn't get stored as fat? I'm wondering why. I know that if a diabetic doesn't take enough insulin, they can actually *lose* weight. Is this correct?

[chasecurry]

The condition=bad
KNOWLEDGE IS GREAT
Solves are all the rage though;)

[singhpooja]

Please sir Hindi me bta sakte hai
Please Hindi me video bnaiye

[FreePalestine-FreeGaza]

I have gone from type 2 to type 1- apparently its the first of its kind. Really wish i had an answer for it