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Spatial analysis of human lung cancer reveals organized immune hubs
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Speaker: Nir Hacohen, PhD, Director of the Center for Cancer Immunology, Massachusetts General Hospital
The organization of immune cells in human tumors is not well understood. We previously showed that immunogenic tumors harbor spatially-localized multicellular ‘immunity hubs’ defined by expression of the T cell-attracting chemokines CXCL10/CXCL11 and associated T cells.
The organization of immune cells in human tumors is not well understood. We previously showed that immunogenic tumors harbor spatially-localized multicellular ‘immunity hubs’ defined by expression of the T cell-attracting chemokines CXCL10/CXCL11 and associated T cells.
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