Imaging brain tumors - 1 - Introduction and classification

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Brain tumors are one of the most common diagnoses addressed in neuroradiology. This covers a wide spectrum of disease, from primary brain tumors like gliomas and glioblastomas to secondary disease like metastases. This lecture covers the spectrum of the most common brain tumors, with an emphasis on primary brain tumor.

This first video discusses how brain tumors are classified, the genetics of these tumors, and a general approach to brain tumors. Tumors can be divided into a few categories, including astrocytomas, oligodendrogliomas, other low grade glial tumors, and common non-glial tumors. Since the WHO reclassification occurred in 2016, genetic information has been used to classify tumors, with the most important mutations being isocitrate dehydrogenase (IDH), 1p19q codeletion, and MGMT methylation. Oligodendrogliomas must be IDH mutants and 1p19q codeleted, and other tumors are now classified as astrocytomas.

IDH mutation is associated with lower grade astrocytomas and is associated with a survival advantage. Similar, MGMT methylation is associated with a better response to radiation, more pseudoprogression, and better survival.

Additional videos in the playlist will address some of the specific imaging findings and forming a differential diagnosis for brain tumors.

The level of this lecture is appropriate for radiology residents, radiology fellows, and trainees in other specialties who have an interest in neuroradiology or may see patients with brain tumors.

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As first year radiology resident, This is so helpful Thank you sir !

hamzamaatoug

Thank you so much for making these wonderful lectures! I am a beginner in radiology and your videos do help me a lot. Your lectures are very helpful for doctors in developing country like me. Please keep up the good work.

minhkhoalam

Thank you for your great clear explanation video. It explains more about my grandmother's glioblastoma. It happened a long time ago, 1987. She was 64 when she passed away.

Miacorr

Naaice! could you pl make one in detail correlating imaging findings in a specific type molecular make up

sleshabhalja

Thank you for such as amazing lecture! This is very helpful. :)

ramitarami

Really good content, but man the voice. contrary what the other comments say, it's not the deep voice which makes is hard to focus on the topic, but the vocal fry. Maybe you can re-record the voice-over without that? It really lessens the quality of your presentation, which is a shame, because it's a great video apart from that!

gregattac

Nicely explained but ur voice is too deep, , 😁

riks

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The voice volume is disturbed and unclear, and your tone truly sounds like you are taking this video recording as a torture when you would be rather doing a 100 different things. Other than that fairly informative. much too brief but thanks.

ot