Imaging brain tumors - 2 - Astrocytomas

Brain tumors are one of the most common diagnoses addressed in neuroradiology. This covers a wide spectrum of disease, from primary brain tumors like gliomas and glioblastomas to secondary disease like metastases. This lecture covers the spectrum of the most common brain tumors, with an emphasis on primary brain tumors.

This video discusses imaging and genetic features of astrocytomas, including low grade astrocytomas (WHO grade 2), anaplastic astrocytoma (grade 3), and glioblastoma (grade 4). By definition, these tumors have intact 1p19q. They can have either IDH mutation or IDH wild type, and IDH mutation is associated with increased survival. Higher grade tumors are more likely to have more mass effect, more enhancement, and less well-defined margins.

Additional videos in the playlist will address the imaging findings of other types of brain tumors.

The level of this lecture is appropriate for radiology residents, radiology fellows, and trainees in other specialties who have an interest in neuroradiology or may see patients with brain tumors.

[bobbyewing]

6:23 my brother's CT looked EXACTLY like that. I remember the doctor pointing with his pen and making markings on the films (this was 2001 so digital radiography wasn't common back then) and showing the splinters that went out from the tumor invading other parts of the brain and he was like "we could remove this tumor and all the spikes but there will always be something growing back because they could never get 100% of them. He had Grade 4 astrocytoma and passed away 3 years after diagnosis. In that time he was able to tour the country with his band, he got to go on trips and meet many famous and important people... He always walked with God and always told me he wasn't afraid of dying. Prayers for ALL affected by cancer.

[alfonsogarfias]

Excellent!!! Clear, Sharp information, and now I love Neuroradiology

[reinapoliakov]

thanks you for the explanations of the classifications 👍

[bonolobusang]

Please make it audible.. your video looks very useful and informative but your voice can’t be completely heard.

[abdullahmonla]

Nice helpful video thank you so much
But the voice pitch! please is not so clear!

[realchestro]

I can't hear a thing :'D sounds like me when I'm hungover. It's really not your fault though, my hearing can be poor.

[delaneyscott]

Hi. I just got diagnosed with an astrocytoma in my right temporal lobe, main symptom being seizures. I dont really know any other details other than it is 8 by 11 centimeters and I am getting follow ups from duke, UVA, and Johns hopkins. If you had to guess, would you think malignant or benign?

[JessM]

I had a grade 2 Astroytoma, I had surgery and 100% was removed, if it were to return would it most likely to be grade 3?

[kavyadoddapaneni]

Hi.My father has been diagnosed high grade astrocytoma in 3rd vertical and left lateral vertical underwent surgery in nov 2021 nd removed only 10% and currently he is undergoing with chemotherapy and he also underwent to radiation after the surgery

[newsdigest]

Seizure from workplace, CT came fine, but MRI got a leson, low grade astrocytoma, now on keppra. Location, Canada.

[henrymeere]

So my mother in law has a anaplastic astrocytoma, honoustly on avg what is the life expectency of this I'm aware she will pass cause of this, but if it weeks or months or years

[mylife]

my family member have a anaplastic astrocytoma grade 3 tumor. doctor operate first time and doctor told us it's completely removed. and after surgery and radiotherapy my family member had patient recovering very fast .but suddenly after 7 monts tumor come back then doctor operate 2nd time and after surgery doctor say it's completely removed.but after 2nd radiotherapy patient after sometime patient became weak day by day .every after 3 months doctor did MRI scan now after one year MRi scan tumor come back .so what the solution of this tumor? patient age 34 years old. plz sir tell me

[bobbbyfirm]

Hi, regarding the CT taking in case 2; how do you differentiate it from the ischemia of brain CT (with loss of grey-white differentiation, may cause midline shift (due to edema?)

Thank you for a good and helpful video

[aygunhuseynova]

low grade astrocytoma is a benign or bad-tempered?

[habibullabava]

sir, I had a non enhansing lesion in left lobe, and removed it by surgery on 14/06/2019_(astrocytoma grade 2 ).Checking by MRI scanning, between every 6months.Now miled increase in lesion, Ie-28cm*30cm*32cm.now in 50years old

[lamborghinidreamers]

Can normal CT scan shows the tumour on our brain.

[nareshj]

Hi one of my family members age 30 MRI has reavled that there is a lession occupying 29 X 22 ×27 mm (AP x TR x CC ) in the pineal region of brain, the MRI study reavals that the lesion occupying space is pineocytoma or high grade astrocytoma . Is this curable with surgery ? And what can we expect about life expectancy

[AMOVIES]

Hi sir My age is 24 Astrocytoma, IDH mutant, WHO grade is Butu p53 (Clone BP5312, PathnSitu): Occasional cells are positive.

[catherinekayne]

Had craniotomy may 1 2024 to find out my tumor on left temporal lobe. No pathology yet

Hello doctor, my question can MRI report scan wrong or missed like CT Scan blurred images? I'm already MRI with contrast injection. I don't know why I have smell senses seizures after 9 years life without seizures, I have Astrocytoma grade 2 history in 2011 and this problem are done with operation and radiation 32 times with Tomotherapy.
In my last MRI scan in March 2020 are clear but in MRI report said no tumour but seems Gliosis Post Op and Atrophy Parahippocampal in lobe temporal right side. I already consult with two doctor but the doctor said I am just epilepsy, meanwhile seizures drug are not make the seizure go away.
The MRI result is that normal without any problem?