RNAi: Slicing, dicing and serving your cells - Alex Dainis

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RNA, the genetic messenger, makes sure the DNA recipe gives your cells exactly what they ordered. But sometimes that means inhibiting some other RNA that got the recipe wrong. This process is called RNA interference (RNAi), and it acts as a self-correcting system within the complicated genetic kitchen of your body. Alex Dainis explains the importance -- and exciting potential -- of RNAi.

Lesson by Alex Dainis, animation by Cinematic Sweden.
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I couldn't understand RNAi well, but this lecture is very clever and help my study so much! Thanks!!!

Before then, I was a little confused by technical terms of this phenomenon.

ichliebemeinfunt
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The cooking metaphor sorta makes it a bit more confusing for me

halcyonparade
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The quality of the animation is sooo good! I'm used to seeing amateurish work in these edutainment animations. This animator actually understands stretch, correct physics, motion blur etc.

secondjoint
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I wish to contribute myself in creating this kind of educative videos when I grow up. This is so much meaningful.

valeriesze
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Great video, best metaphor ever and I like the cute animation

XENOS
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Moral of the story,






Chop up unsatisfied customers.

jack
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This is the best explanation out there. Thanks a bunch! Really appreciate it.

kristiabondoc
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Amazing communication of science in this video!

asapelliott
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The voice has perfect timing to understanding.

jakeshmohapatra
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Let me summarize everything in one shot ( actually this is the project that I've been assigned)
So rna interference is basically used to prevent gene expression ( prevention of translation and hence production of proteins )
So to do it artificially we use vectors and introduce the desired dna . Now this dna produces both sense and anti sense strand these being complementary to each other bind together . Dicer proteins sense these and chop them and these thereby approach the m rna and slicer protein comes and chops down the m rna too
So, viola ! We've successfully prevented the gene expression

beartheburn
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What a classic video. I watched this video when I was studying for my MCAT and now I am in medical school, studying for USMLE Step 1 and came across an RNA question and it reminded me of this. Thank you so much for these videos!

knosis
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That RNA decking the other RNA caught me off guard and had me bustin up!

veryawful
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too good difficult concept discussed very easily

kirtikasaxena
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Where were you when I was looking all over YouTube to understand rnai for my biology test yesterday 😭😭😭😭😭😭😭😭😭😭😭

ume
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this video is 4 weeks to late. tried to understand it for an exam, but the information given was too confusing. this video sums it up perfectly :)

FrankyFiks
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This video is awesome! Its so informative! Good job alex!

SciFiles
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Congratulations Alex! What an accomplishment...

PeterDosRamos
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Wow I didn't know Alex Dainis narrated a Ted-Ed video !

aminoddindomado
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Trying to make it relatable, you guys screwed with the explanation 100 times more!

thetypewriterbtch
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wow Alex! That is way cool. You are certainly making an impact! Thank you!

judonomobic