Gene Silencing by Micro RNA - Medical Animation

MicroRNAs are a class of small, non-coding RNA molecules that regulate gene expression by inactivating messengerRNA (mRNA) and have a big impact on many biological processes. This medical 3D animation shows the biogenesis and function of microRNA within the cell. The goal of the project was to arouse interest by presenting the topic of gene silencing in a simplified and visually appealing way. It was part of my master`s graduation project where I had the opportunity to combine my two different studies Information Design and Molecular Biology.

CREDITS:
Narrator: Steve Crilley

[glenndavis]

Boy, did this information become suddenly far more relevant today. Appreciate the factual information.

[natehawkins]

We are indeed fearfully and wonderfully made.

[TheSoundWave]

This is absolutely fantastic, not only is the information very easy to absorb, but the animation style and overall design is amazing! As a lot of comments have said before me, I very much encourage you to make more scientific animations like this!

[tedmccarthy]

I'm a Mechanic and this is fascinating. It's another world within a cell. Hopefully now that we know how it works. Man will not mess with it without fully understanding it for the sake of Money and Greed.

[Mrjmaxted]

This animation is amazing and you should definitely make a series of these covering other important topics. What a great little crash course on the key points of miRNA this was!

[AshenLanka]

It was really hard for me to study this mechanism by reading a book. But you made it so clear & easy for me to understand as well as memorized. Thanks a Lot! Worth A Big Hats Off! :)

[kdbublitz]

Every time I see things like this I am fascinated and in awe of how complex we are... weather we were made by a higher power, or randomly converged in perfect circumstances, I appreciate our existence.

[Alarix]

I feel compelled to react as well - videos like these are breathtaking and great for grasping the concept of mRNA. What is unusual is that almost every screen breeds more questions - like no other topic! Especially my questions are about those parts that get discarded along the way - why is it cut? Why was it discarded? What happens to the discarded mRNA part? What happens to those carrying it? How do these proteins move (seeing they have no obvious propulsion mechanism) and how do they know where to take the mRNA strand from and where to paste it? What happens when the person moves or shakes or is massaged by a vibrating instrument? It is mindblowing.

[MichaelHarrisIreland]

Thanks so much, I'm an old man and haven't time to learn any other way but this way. The video is absolutely amazing. I've already seen many videos on cells and they are more magical than the Santa Clause I once believed in. The world is far more mysterious that I could have imagined.

[JehJehYoutube]

Very well organised and structured video. Animations were clear and concise and there was enough information in this video to have a good understanding of microRNAs.

[millard]

Only wish more videos like this were there, , , , this is how people can understand cell biology

[Therradican]

It will be nice to see the effect of COVID vaccines to RNA

[noxfox]

This is so interesting and instructive! Totally beyond topic for what I'm supposed to be studying as a first year nurse student, but it really strengthens my understanding of DNA and RNA, to better comprehend what I'm studying, fill in the gaps in the literature I have. For every new thing I learn, so many new questions arise ♥ Props for the beautiful animations with just the right amount of jiggling to feel the chaotic activity without it being disturbing to take the knowledge in!

[alexandrajanczewska]

Katharina, you are a SCIENCE GODDESS. Like other viewers, I've had a lot of trouble visualizing this process, and even more trouble pinning down a succinct, clear explication of it on the internet. You're doing fantastic work! THANK YOU.

[francoisriche]

This is definitely the best video so far. I've watched several so far and this one is the most comprehensive in both explanation and visuals.

[mohcinemabsoute]

The first time in my life i heard about this and it amazingly explains all the cells diversity in our bodies.

[slendrmusic]

probably the best animation on this topic

[adonaiblackwood]

Wow! The Gain of Function possibilities! Imagine the future for this patented technology!

[flyingnone]

Very nice presentation.. how does the mRNA they giving people nowadays in shots go with this ?

[aliyashams]

This is amazing Katharina. A very big thank you for making it so easy to understand.