How to Breakdown a Question | USMLE Step 1 | Hematology

How to break down a USMLE Step 1 question, from MedSmarter with Dr. Jason Colip.

The attached video is the breakdown of another question regarding Hematology.

A 75-year-old woman with asthma presents to her primary care physician for an annual check-up. The physician performs a physical examination and orders routine blood work, which reveals a macrocytic anemia. Subsequent laboratory tests show an elevated serum methylmalonic acid level. A peripheral blood smear is shown in the image. If this patient’s vitamin deficiency is not corrected, what neurological symptoms is she most likely to experience?

(A) Confusion and confabulation
(B) Deficiency in this vitamin does not cause neurological symptoms
(C) Dysarthria and diplopia
(D) Paresthesias and ataxia
(E) Syncope and lethargy

We break down the concepts in simple terms in shorter videos so students can focus on the Educational Objective to get a deep understanding of the concept.

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Jason Colip, MD - USMLE Instructor
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