How mRNA Vaccines Work | Penn Medicine Explains

Vaccines are about to change the world...again. The scientists who first developed mRNA vaccines earned a Nobel Prize in 2023. mRNA vaccines are used to help battle COVID-19, and have the potential to eradicate diseases like HIV, herpes, sickle cell anemia, and even cancer. Learn how the vaccines work and where the technology could be headed in this explainer video.

The Pfizer-BioNTech and Moderna vaccines for COVID-19 use the mRNA (messenger RNA) technology developed at Penn by two Nobel Prize winning scientists: infectious disease expert Drew Weissman, MD, PhD, and his longtime research collaborator Katalin Karikó, PhD, an adjunct associate professor. Dr. Weissman has been studying mRNA vaccines for decades. This technology could change the way future vaccines are made to prevent countless other diseases.

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[seamuswarren]

Is this the cut ‘n’ paste editing enabled by the CRISPR process?

[carasmussen]

explained very well and easy to understand a very complex process

[justfootballacademyaustral]

Why has there never been an approved mRNA vaccine prior to now, if it has been in development for so many decades?

[Dfynfyimgtbjufjiyffvjogfsdgyjb]

Do mRna available for herpes simplex ?

[Oh.its.multiple]

This is amazing! Tomorrow I'll be receiving the Moderna vaccine for COVID, and I'm beyond amazed on how this vaccine is created. I honestly can't wait anymore. Thank you so much to every scientist, doctor and team that helped to produce this, and makes it possible to vaccinate everyone. Ya'll rock!