Cancer-busting vaccines are coming: here's how they work

Most vaccines work by teaching the immune system to recognize harmful viruses or bacteria before a person gets infected and becomes unwell. A few cancer vaccines do this, too. For example, a vaccine is given to young people as protection against human papillomaviruses that can cause cervical cancer.

But scientists are also developing cancer vaccines that could be used as treatments, after cancer has been found.

These vaccines work by teaching the body's immune system to distinguish between healthy cells and abnormal cancer cells. To do this, researchers need to identify proteins that are made by cancer cells but not by healthy cells. These proteins can be used like a barcode. The vaccine teaches the body's immune cells to 'read' the barcode, as a way of identifying the cancer. This video explains how these vaccines are made, and the pros and cons of various types of cancer vaccine.

[sunflowerz]

If they work it will be a miracle for mankind!!! My entire family has died of the dreaded C

[djinn]

This would be one of the greatest breakthroughs in medicine history!

[carlosnino]

This is more complicated than show. Every cancer is different, so we have developed vaccines for some cancer, not for others. But this is exciting and everyday we make progress!

[fumiyafuse]

I wish im still alive if this comes. I have cancer stage 3

[gf]

Hurray for science! Hurray for scientists!

[Eric_Malbos]

Very well illustrated and informative video. There are already some clinics which propose such personnalised treatment for activating dendritic cells. However, the cost is rather high as mentioned. Hopefully, with automation and diffusion this cost will decrease over time.

[songnverse]

Haven’t we learned anything from current mRNA technologies?!?!

[footfault]

Amazing progress at molecular level researches! Commonly shared strategy is to help our own body or immune system to combat. That is, scientists get more, wider & deeper knowledge about organisms including ourselves!

[maestoso]

Scientific journals need to improve their reputation. Continuing to be given funding from companies (like Moderna in this video) really exposes the conflict of interest.

[btsmochimi]

Oh I live in a time to see this....what an honor❤😊

[CraigDSouza-xote]

Couldn't the insitu method also trigger auto-immunity? Because radiotherapy will also rupture normal cells and their proteins, exposing them to the activated dendritic cells.

[pwndpp]

Short and precise video. Loved the overview and animations of methods used for soon-to-be treatments. 🙌🏼

[CharlesCurran-mp]

I don’t know if this will ever be released. Too much money in keeping you sick.

[nicholasgordon]

There's one thing about this that makes no sense to me: if cancer antigens and neoantigens are already present in the individual's body, why does the immune system not recognise them in the first place? What good does extracting the proteins and reinjecting them do? I feel like this video is missing something out.

[Anythingforfreedom]

This is how every zombie movie starts.

[alexbowman]

Chemotherapy was developed after the gas attacks in the First World War were noticed to attack only specific cells and some modern chemo drugs are still WW1 gases.

[archael]

Something great to look forward to in 2085!

[truthforthemasses]

The sound effects were so soothing to my ears.

[BobbyJobling]

But...

"Hyperprogressive disease in lung cancer and other tumors is an urgent clinical issue affecting 1 of 5 patients treated with immune checkpoint inhibitors (ICI), affecting their prognosis and leading to death in a very short time. As the use of immunotherapy increases in the clinic, it is important to understand the intricacies of this new treatment option to optimize treatment approaches."

[John-jsgk]

Where does the cancer come from? Covid mRNA vaccines.