COVID-19 spike protein vs. vaccine spike protein: key differences | Dr. Rhonda Patrick

There are about 26 spike proteins on the surface of each SARS-CoV-2 viral particle that help the virus enter and infect cells. The spike protein binds to the ACE2 receptor and undergoes a conformational change from a closed or pre-fusion conformation to an open or post-fusion structure (as it fuses with the cell membrane). Some people surmise that if the viral spike protein is dangerous — because it allows the virus to enter cells — then vaccine-related spike proteins render vaccines unsafe. COVID-19 vaccines contain different spike proteins than the SARS-CoV-2 virus. All vaccines used in the United States contain two extra amino acids that lock the spike protein into the prefusion conformation, such that it cannot fuse with the cell membrane. In this clip, Dr. Rhonda Patrick describes what distinguishes viral spike proteins from vaccine-related spike proteins.

Original episode posted Sep 17, 2021.

[FoundMyFitnessClips]

*Watch the full episode:*

*FoundMyFitness episode page:*

*More clips from this guest:*

[brianhoward]

Big fan of DR Patrick, but I have to disagree. The burden of proof is NOT on us to prove it’s dangerous. The burden of proof is on the pharma companies to prove that it’s NOT dangerous.

[dano]

…wouldn’t it follow pretty logically that there should have been a study specifically on whether mRNA derived spike does anything we don’t want it to? I.e does mRNA derived spike from vax cause down regulation of ace2? Are there any studies available so far? Not to mention other stuff like what about people with peg antibodies what does it do in them etc. folks got enough data in 6 months to flush this out? If I was a moderna shareholder I’d be livid what have they been doing since 2013 not being able to bring a drug to market if it was suddenly this easy?

[maxxtheautumn]

Is this vaccine against SARS-COV-2, or is it against its spike protein, or is it against some other random protein? I'm confused. If it's not that important to replicate the spike protein precisely to 'tune' the immune system to recognize it, then why Delta variant rendered the vaccines less effective?

[nobodyimportant]

So, what happens if you’ve contracted the COVID virus and then get the vaccine?

[genshinFPlay]

"All vaccines used in the United States contain two extra amino acids" anyone can tell me if this is the case with astrazeneca ?

[James-zuij]

Is the AstraZeneca spike protein the same as the Pfizer spike protein

[steiraman]

Very much the dose:
Defined small dose in the arm vs. viral replication in the lungs

[hillaryclinton]

So.. my idea of givi g extra ace2 receptors is a good one?

[bvons]

if the spike protein is so dangerous, then I think it makes sense to get inoculated against it. This simple logic seems to be missed by those that are so concerned about the evil spike protein.

[bludog]

Thank you Doctor Patrick, you are an inspiration to me, (someone who has been very standoffish with this vaccine.

[pauldoan]

Excellent thats what I was feeling that the spike protein was different in the vaccine your explanation was very helpful and easy to understand thank you .

[SamSam-pomk]

Thank u for this info Dr god bless you and your family

[almostthere]

Dr Rhonda Patrick is a amazing person.. she’s amazing I wish I could think of other words to describe her. I appreciate her and trust her word.. and that’s saying a lot these days muah please keep going.. I am a personal fan I don’t watch everything she does, but when I do. She explains in a way, where it’s so easily understandable..

[sonofjay]

Man. This is the first thing I've heard that may could have swayed me to get the shot if I hadn't already had covid-19

[jacquesjacques-yhhh]

Very clear explanation from an high level