Dial in the best conditions - Automated chemical reaction optimization

Development of safe, scalable and robust synthetic processes is an essential step in chemical development. Considerations may include yield, selectivity, enantiopurity, volumetric productivity and process mass intensity (PMI). Additionally, laboratory experiments may include routine and manual experiments such as range finding or fate-and-purge studies. Automated workflows are impactful to identify global optimum process conditions for a given target transformation, and parallelization of reactions removes manually laborious experimentation in the lab. This enables more work to be done with limited time, resources, and staff, and frees up scientists for higher value-added activities. Additionally, automated workflows adds precision that results in superior datasets for building process models.
In this webinar we will discuss:
• Application of automation to DoE and QbD strategies for process optimization
• Integration of reaction design software with execution hardware
• A case study to demonstrate how customers are using this in the real world