The Science of Alzheimer's: Brain Awareness Week 2023

Learn about the challenges physicians face in treating Alzheimer’s disease, what happens to the brain as the disease progresses, and current research on neuropathology and cell types in health and disease.
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Alzheimer’s disease is the most common type of dementia and leads to devastating cognitive and neurological deficits. However, despite affecting an estimated 6.2 million adults in the US alone, its causes are poorly understood, and no effective treatments exist to halt or reverse the neuron death caused by the disease. How the disease starts — and what happens in single cells and different cell types across the brain as the disease progresses — is similarly unknown.

The Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD) consortium is a research collaboration headquartered at the Allen Institute, with additional research projects at UW Medicine and Kaiser Permanente Washington Health Research Institute. These researchers are investigating the foundational science of Alzheimer’s – what happens in different brain regions, in individual cells, and across different types of brain cells in this disease, ultimately hoping to pinpoint the disease’s causes and new targets for better therapies.

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All really good talks about Alzheimer's disease science for non-experts audiences.

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Ive got Alzheimer's disease myself, Ive been an alcoholic for 30 years which doesn't help, stay away from anything with aspartame in it and aluminum products, my daughter showed me this video. Idont know how long shes been talking care of me i have 3 beautiful grandchildren and i cant remember any of their names from time to time she showed me pictures of them. Thats how my mother died at 93 i don't want to go out like she did, i became a mean bitter oldman not a day goes by where i don't tickle the roof of my mouth with a .44S&W, i have to stash it away from everyone. i hate the pharmaceuticals in the US i refuse treatment. I don't remember anything from my life. My daughter keeps showing me pictures and videos of a happy family going fishing and traveling and camping with my 2 daughters and 1 son with my wife all of them smiling so sweetly, I dont remember any of it. Seeing in pictures and videos of myself younger and fit with a loving family going swimming and fishing and hiking and hunting and bowling and hockey games, not remembering any of it saddens me greatly. How can i forget such joy. My wife died 5 years ago in my arms at 75, i loved her so much more than anything in all of existence, we will meet again soon . Im 81 and in constant pain cant wait to finally meet her again but im scared i won't remember her face. Ive been drinking sence i was 54 then i started drinking heavily for the pain. Dont rush life, every moment is worth you're wait in gold. Love everyone and everything for the present is the best time you'll ever experience. Dont push away any loved ones for the relationships with them only comes once in a lifetime. Doctors say i got eight to twelve months left but i cant wait that long. My daughters show me pictures and videos of my other kids but i don't remember them. She was my first born and is the nicest soul anybody would ever meet. Im only holding on this long for her and her kids, ive sent one of them off for college im so proud of my grandson Liam, hes going to be an engineer in Computers.

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mice dont drink as much water as we do lol