What is Insulin Resistance? | Jason Fung

What is Insulin Resistance? | Jason Fung

🔍 Demystifying Insulin Resistance: Unveiling the Connection to Metabolic Health 🌐
In this enlightening video, we embark on a journey to unravel the intricate web of insulin resistance and its link to metabolic syndrome. Key insights include:

🔄 Insulin Resistance & Metabolic Syndrome: Understand the pivotal role of insulin resistance in the development of metabolic syndrome and its impact on overall health.
🤔 What is Insulin Resistance?: Delve into the fundamental concept of insulin resistance, exploring how it disrupts the body's normal insulin response.
🌌 Internal Starvation Paradigm: Explore the paradigm of internal starvation and how insulin resistance contributes to metabolic dysfunction.
❓ What is Type 2 Diabetes?: Gain clarity on the relationship between insulin resistance and type 2 diabetes, unraveling the intricacies of this prevalent condition.
📈 Hyperinsulinemia: Examine the phenomenon of hyperinsulinemia and its connection to insulin resistance, shedding light on the intricate balance of insulin in the body.

Join us in demystifying insulin resistance, exploring its implications for metabolic health, and gaining valuable insights into its connection with type 2 diabetes. Hit the like button 👍, subscribe for more insightful content, and ring the notification bell 🔔 to stay informed!

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▶️ Timestamps / Chapters
0:00 Intro
0:15 Insulin Resistance & Metabolic Syndrome
0:48 What is insulin resistance?
3:18 Internal Starvation Paradigm
4:30 What is type 2 Diabetes?
8:09 Hyperinsulinemia
10:38 Outro
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📌 BOOKS:
👉 The Obesity Code - Reviewing underlying physiology of weight loss and how low
👉 The Diabetes Code - Reviewing how type 2 diabetes is a reversible disease and
👉 The Cancer Code - Scientific exploration of how cancer develops -
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📌 YouTube Medical Lectures (for specialist physicians):
▶️ The Roots of the Obesity Epidemic: https:
▶️ Therapeutic Fasting - The Two Compartment Problem: https:
▶️ Does Calorie Counting work?:
▶️ Two Big Lies of Type 2 Diabetes:
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#WhatIsInsulinResistanceJasonFung #WhatIsInsulinResistance #InsulinResistance #wightLoss2023 #jasonfung #drjasonfung #drfung #fung #nutrition #diet #health #fasting #intermittentfasting

[seattlebeard]

Jason Fung, Pradip Jamnadas, and Eric Berg changed my life. I've lost almost 100 lbs in seven months. All my blood tests are perfect, and my doctors are thrilled. I'm 61 and thought I'd never lose the weight. If I can do this, anyone can.

[panaceiasuberes]

Around the time The Obesity Code came out I was on my way to bariatric surgery. But the annexes of that book really changed my life. Went from 200 to 120kgs in 8 months with fastings from 5 to 44 days whilst leaving fructose out of the diet.

Today I have a new life thanks to Dr. Fung.

[JayNa]

I cut off carb and sugar, plus intermittent fasting for 2 months. I was 5'3" 170lbs and now, 144lbs!! This really works!!

[mirzamanmirzaman]

The worst news I heard in my life was when my clinic doctor told me “ you are prediabetic”.A1c was 5.8, Glucose was 260 and my weight was 201 lbs. I wasn’t able to read news and emails in my phone because my vision was week and blurry. I was very upset and hate the word diabetes because my parents had it and they both passed away. My two brothers have diabetes taking ( Glucophage tablets) after every meal. My doctor didn’t tell me anything about insulin resistance. I came home and started thinking. I found Dr. Jason on YouTube watched his videos repeatedly and decided to implement his advices practically. After eight to nine months, I lost weight, A1c dropped and triglycerides, cholesterol became normal.
I reduced carbs intake and eat twice a day only. I have a normal health and never think about diabetes anymore.

[Messiahwalter]

Dr Jason, Berg, Pradip should receive the special Oscar of YouTube !!! Starting fasting few weeks ago …. Today my numbers are perfect …..first time in 15 years !!!! Unfortunately I followed for years the wrong direction of the $$$$ medical business and that took me to the ER with 4 bypass surgery!!
The good news is : it is never too late 👍thank you gentlemen

[andorandor]

finally the first person who explains why the resistance happens, thank you!

[PK-cjpg]

This video can save life! Especially for those who are treating their diabetes WRONGLY! Fasting is the right way to do instead of putting more insulin into the body.

[maricelg]

Happy Sunday, Dr. Fung and to everyone watching. Stay happy, healthy and wise 🌸🤍🎀 Have a great day

[LTPottenger]

Some of the many benefits of fasting and low carb diet on the immune system, blood pressure, blood sugar and anti-aging, all backed up by clinical data:
Thymus stem cells are regenerated, which suppresses aging and renews the immune system.
Fasting stimulates phagocytosis, the ingestion of bacteria and viruses by the immune system.
Blood pressure is quickly and dramatically lowered, which is very important for a good outcome with the current pandemic.
Fasting increases nitric oxide, which has manifold postive effects like reducing arterial plaque.
Weght loss from fasting only loses10% lean tissue and 90% fat compared to the typical 25% lean tissue and 75% fat lost when calorically restricting for long periods.
Blood clotting is reduced and blood clots and arterial plaque are reabsorbed into the body.
Vitamin D plasma levels are increased, and vitamin D in turn increases autophagy!
Blood sugar and insulin are lowered, allowing white blood cells to move more freely throughout the body and do their job. Ideal blood sugar is around 80. Some viruses activate glycolosis (the release of sugar in the body) and clinically it has been shown that decreasing glucose metabolism in the body weakens the influenza virus.

The hormone Leptin is an immunomodulator that keeps the body from attacking itself and obesity causes leptin resistance. Fasting very quickly reduces leptin resistance and leptin levels and one day of fasting can cut your leptin levels in half and gets your immune system working properly again!

When you move out of MTOR your body shuts down the building blocks of the cell which are used to produce organelles and proteins. This means the mechanisms needed by viruses to replicate are by and large unavailable when you are in a deeply fasted state.

It stimulates the AMPK complex and activates autophagy. Autophagy (literally self eating) will cause cells to recycle foreign matter such as viruses and kill cancerous and senescent cells. AMPK does many helpful things in the body including activating the body's antioxidant defenses.

Deep ketosis virtually eliminates chronic inflammation in the body. This can offset the life threatening symptoms of viral pneumonia which effectively kills you through inflammation. This also creates BHB ketones in your body, which also help your immune system and anti-oxidative system, especially in the brain. Ketones also provide an additional energy source during infection, which is critical when trying to fight off a bug. In fact you can have as much as three times the total energy available in your blood when you are in deep ketosis, or even more.

It increases mitochondrial function and repairs mitichondrial DNA, leading to improved ATP production and oxygen efficiency and thereby making cells better able to fight off infection. Increased mitochondrial function also has the added benefit of increasing your metabolism and cancer prevention!

Your body releases interferon which is also triggered by the body during viral attacks to shut down the replication ability of the surrounding cells and stop infections.

After 72 hours or more fasted, your body actually recycles large numbers of immune bodies and creates new ones, rejuvenating your entire system.

When you fast, this stimulates apoptosis in senescent or genetically damaged cells. This kills these cells off completely. Senescent cells are responsible for the effects of aging and are the root cause of the development of cancer. If it were possible to destroy them all it would completely stop aging and cancer. That is not possible but fasting can help limit these effects by killing off many of the affected cells and limiting the future effects of aging.

Fasting also releases BDNF and NGF in the blood which stimulates new nerve and brain cell growth, helping a great deal with diseases like MS, peripheral neuropathy and Alzheimers.

In fact, the biochemical precursor to BDNF is beta-hydroxybutyrate, which is the same ketone the body produces to nourish the brain while fasting.

Autophagy induced by fasting even helps hair regrow.

Dieters losing weight through intermittent fasting show greater reduction in waist size and increase in insulin sensitivity for the same weight lost and alternate day fasters were shown to lose fat while gaining muscle at the same time over a six month period.

Fasting has been shown to increase bone marrow volume by 10% and levels of carnosine in the body in as little as a few weeks.

Fasting also increases telomere length, negating some of the effects of aging at a cellular level.

Eating one meal a day can bring most of these benefits to a lesser degree, and adding a few entire days off from eating per week will have even more effect especially when starting to feel poorly.

Exogenous ketones can aid with fasting, making it easier in healthy people and allowing some people with specific issues to fast in spite of them without worrying as much about hypoglycemia.

Children, pregnant or nursing women should not fast for periods longer than 16 hours. People with pancreatic tumors or hypoglycemia generally cannot fast at all. Type 1 diabetics can also fast but it is more complicated and should be approached with caution. Those with Addison's disease may also be unable to fast without liberal use of exogenous ketones, depending on severity. If you experience extreme symptoms of some kind, especially dizziness then simply break the fast and seek advice.

Resources:


This list compiled over months of research by the user known as Pottenger's Human on youtube but feel free to copy and paste this anywhere you like, no accreditation needed!

[dalaov]

This by far the most clear and easy to follow video on what insulin resistance is.

[ali_plz]

I wish nursing instructors explained things this way! I’ve been a nurse for a while now but never really understood how insulin resistance happens. Thank you Dr. Fung! 🙏🏻

[KulwantSingh-xrsi]

Anyone else just watch these on Sundays to support the Fungster even thought they already know everything to be covered?

[ohui]

Thank you Dr Fung. Two months ago my doctor said I am pre diabetic and I decided that getting myself back on track is my new challenge, and so I started researching into what I can do to help myself. I have heard from friends that type 2 diabetes is not curable and that people would get fat and overweight and so on, and that I will end up taking more and more medications as there shall be side effects with more medications. I don't want any of these! I came across one of your videos and it was easy to understand and logical. I started the 168 regime on Oct 18 (today is Dec 14) coupled with low carb low sugar diet and my weight dropped from 160 lbs to today's 141.5lbs, body fat went down from 23.3% to today's 19.6%, BMI went down from 24.4 to today's 22.5. a1c went from 6.2 to 6.1, fasting blood sugar dropped from 6.8 to 5.7, total cholesterol went from 6.2 to 5.2. Btw my six packs finally showed, and I had to get new pants as waist went down from 35inches to 31.5 inches. It's as though I have a different body! I shall continue 168 intermittent fasting and low carb diet as a lifestyle as it is easy to follow and sustainable. There is also the time savings and food expenses. Now my decision about whether to eat is simple: when outside the feeding window then don't eat and even if inside feeding window if not hungry then eating is optional. Thank you so much for your videos and you have changed many peoples' life's including mine.

[lassaad]

Give this man the Nobel Prize! Thank you for your passion to help others, Dr Fung. I’ve benefit greatly from your talks. 🙏🏽

[Knight]

No idea why most first line physicians don’t know this, or don’t believe it. Even endocrinologists preach “smaller portions and exercise” not the “WHY” that works. Dr. Fung rocks!

[daniellejohnston]

This is absolutely the answer. In my life I have worked so hard to control my weight and to lose weight over and over. I was pushing and depriving my body over and over, only to watch the scale stall or watch my body actually gain weight. This process of reducing my blood glucose AND my insulin levels by time-restricted eating has unlocked my fat cells and they are now responding to all the exercise and good food choices. With opening and closing my feeding window each day as you describe, my body is now using the stored energy, and I am eating a delicious low-carb selection of foods that is highly satisfying. This is a workable and relaxed lifestyle that is also normalizing my weight. I am so thankful to find your research BEFORE I had Type 2 diabetes and before the additional weight caused other health problems associated with obesity. I can not stop explaining this process to others, and it is working for them as well, hoping this solves the crisis of obesity-related illness and helps many people to enjoy their lives free of disease. One only needs to study how obesity effects every process in the body to be motivated to make the changes necessary to maintain health. This process you have explained absolutely is the golden ticket. In my clinical time as a nursing student, I observed too many people who were dealing with serious illness that was lifestyle-related and curable. Treating symptoms and not providing solutions for the patients seemed to keep them on a never-ending hamster wheel. This protocol which you described, can push back the wave of people caught in chronic illness and release them. I have read all your books, I have bought your books for others, I will continue to share this important information everyday as my own experience illustrates that it works! Thank you for getting this information out in book form and for lecturing constantly to the medical community about this solution.

[gcortorreal]

Dr Fung, thanks so much for such a nice, logical and easy to understand explanation of insulin resistance. This knowledge will help me decide how to best attack this problem.

[iouliavvedenskaya]

Dear Dr. Fung, I wanted to thank you very much for giving me the courage to start intermittent fasting for life! I am following you since the beginning of August 2021 and watch your instructional and inspirational videos regularly. I am 5'10'' and, as of this morning, lost 40 lbs in 4 months. Thank you from the bottom of my heart! YOU DO DO DO REALLY HELP

[MinuteBody]

Insulin is the hormone that makes a obese, sick and tired. Following a keto and even sometimes carnivore diet I have completely reversed my debilitating anxiety. It's more than just weight loss, it's changes people's psychology🤓

[jlr]

Best explanation ever. Thank you so much, I was diagnosed with Type 2 Diabetes about 2 months ago, after watching your videos i got on a low carb high fat diet and lost 27 pounds. After about the 3rd day my symptoms went away. Been feeling great ever since. Love your videos