What is Lactate and Lactic Acid?

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PATREON

[Anesthesiology]

My favourite biochemistry channel, thank you 🙏 the concept of SID is not undisputed

[kwikitti]

Thank you so much for creating these excellent slides and explaining this metabolic pathway so clearly. I learned a LOT and took a page of notes to help me pack it into my brain. On to part 2!

[Optimization_Coach]

I add baking soda pre intense exersize... amazing difference! Thanks for the clarity here!

[mitch.bernier.coaching.library]

This was a great explanation on SID. I just finished Lactate Shuttle Theory and was looking for a description on SID. Thanks

[BoredT-Rex]

I have been googling this topic all day and despite reading numerous medical journals and articles, and everyone's definition of lactic acidosis, lactic acid, and lactate are all different. I am in the medical field. This is something that actually could make sense. Thank you I owe you my life. electroneutrality in the plasma nice. so basically it should be called lactate + hydrogen ion acidosis, not lactic acidosis

[corwynwarwaruk]

Oh where is the next video! Can’t wait to watch it!

[yasminhusain]

Thank you, this is exactly what I was wondering about

[scuti]

Lactic acid has a hydrogen ion and would disassociate into lactate and the hydrogen ion.
Decreased pH in the blood is due to the maintenance of electroneutrality (balance of cations and anions lactate is an anion). Exercise throws it out of balance. Cations need to be added to balance it out (hydrogen ions- and thua the pH drops).

[Veto]

So it does decrease pH, just not the method that we thought.

[nestorlopez]

The principle of electroneutrality is interesting, but my question is if we know that physical exercise tests the blood lactate from where the hydrogen ions come from to maintain this balance?

[yigozer]

First of all, thank you for such a great and informative video. Are there any researches you can provide for the theory which concludes that after glycolysis, "lactate" is produced, not lactic acid ?

[austcorn]

I’m a bit confused and haven’t been in a chemistry class for awhile if anyone could help. If hydrogen ions are increased in order to maintain balance from increased lactate, why does the PH level drop instead of returning to neutral? Do hydrogen ions just have a greater affect on ph than lactate at their stabilized amounts?

[davidsweeney]

so where does the extra [H+] come from? hydrogen ions just hanging around in the blood, maybe on plasma proteins? Thanks :)

[elam]

If the H+ come from blood plasma proteins is used to produce electroneutrality, why the PH drops then?

[Maryjcorder]

The more I learn, the more I realize how much of what I thought I knew is incorrect :/

[americaniron]

Thank you so much for linking this video in your 2nd part description 😫💪