The Truth about Lactic Acid

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Does lactic acid exist?
Does lactic acid cause muscle fatigue?
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Didn't understand a word until he said mitochondria, bringing me flashbacks of middle school science class "T H E P O W E R H O U S "

Madderthanjoker
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That was so effectively explained and thoroughly broken down, I feel so enlightened lol. Thank you Dr.

stewartwells
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Mom here, thank you for such a thorough and well explained process.

Sheperdsdaughter
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thankyouu that was really helpful you simplified the whole process! much simpler than the text book

nathalieaiad
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I know I am late to the game with this lecture but this comes from after a discussion I had with a prof today who mainly focuses his lectures on early 1980's papers. His lecture was all about lactic acid and I asked about whether he had heard the argument between whether lactic acid exists in glycolysis or not. However I could not find a lot of papers backing up what I had heard in a previous uni course in metabolism where my previous prof had stated the same hypothesis as Dr Mike (it is not present and we should stop referring it as lactic acid). Would be great if I could have some links to papers or authors on this topic.

aliciabryan
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Hi Doc, what an interesting explanation! Can you please provide us some links to references about this. Because this is such a new thing for me. Thank you!

nabilasyahidnaamelia
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Nice video. It's worth getting the oils from Weedborn, though.

shantelleadeline
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great!👏
I have been looking for such a video for a while.🤓

kianas
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I have been telling students about the misnaming of lactic acid for years. My physiology teacher explained this to my class back in 1999. Many times when I would mention this people would laugh at me, even my fellow teaching colleagues. In the following years a lecturer of New Mexico university also spoke about lactic acid misinformation during seminars for the Filex Fitness Convention. It amazes me that 25 years after I was first taught this, many people still believe the incorrect explanation.

ginaferraro
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Excellent brief explanation. Very well done, sir.

phil
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Very interesting! Hadn't learned that before.

rebeccafurse
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I think stuart proposed in acid-base that the strong ion effect of lactate is what makes blood acidic, despite lactate being a conjugate base.

comradejames
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FANTASTIC video. Could you provide some sources I could read? Thanks.

nolikeygsomnipresence
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Reminds me of athlene x. I look it up to find everything I know was wrong!
Do you think there is some benefit of eating not necessarily vegetarian diet, but a base pH food diet? If you eat a lot of acidic food when your body be acidic? I wondered if that would contribute to a longer muscle recovery period.

reptilesgamers
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So if Lactate is being produced to buffer the H+ ion ... doesn't that mean it will bind to the H+ ion and become lactic acid?

TheRealMorgs
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Ya out here in the real world your patient with liver failure will develop lactic acidosis - a high anion gap metabolic acidosis. You can't just act like lactate is good for them, or that the extra hydrogen on what used to be pyruvate is harmless. You must intervene to prevent an arrhythmia by raising the ph of the pt by whatever means makes most sense clinically. Then, you continue to respect the lactate by consistently checking the pts changing acid base chemistry.

What makes your muscles sore is the process of anaerobic glycolysis. The cell will become acidic - primarily buffer out - but continued use under an increasingly acidic environment will cause cell damage and an inflammatory response. Your nerves activate/perceives pain via the presence of cytokines (IL-1 from TNF-a) and other subsequent immune responses. Your nerves are literally sending signals as the cytokine receptors on their cell surface encounters a concentration of cytokines sufficient to create adequate calcium concentration in the dendritic bulb.

The issue I have with taking advise from youtube doctors is that most have about a 20% understanding of how the body works as a system, and without full mastery of the topic they just produce blaze half truth content. This topic is harmless, you are right but in part by chance, and having the general public use lactic acid as a way of conceptualizing how to avoid injuries and how to recover is ultimately much more helpful than harmful. But, hey these PTs do look a hell of a lot better than me with their shirt off.

Source - look up any book or chapter on nocioception. I don't even practice this type of medicine and after 10 years I was able to quickly explain the above - remember you are who you listen to.

Theiliteritesbian
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Thank you for such an informative video of course you’re just one source may I ask where you got your information? and could you post the following links for further review of this new theory. Thank you doctor

TinCupChalice
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Fantastic lectures, please could you talk about haemostatsis
and coagulation.
Thanks
Wendy

wendyhines-randle
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The liver only stores very important things in those ratios, lactate seems good.

manmeetsingh
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People needs to blame it on something. I blame my muscle soreness when I exercise to my years of being inactive and being a couch potato. Lmao

icouldntthinkofagoodname