A1c EXPLAINED | What is it, and why should I care?

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[PowderChaser]

Sir, you continue to be the key glue to understanding concepts and especially to tie them together nicely. This is so valuable to med students and I personally thank you!

[lisa-rouletlawfirm]

This video is so helpful! Love how you explain that high blood sugar turns heme into an AGE, which triggers NOX and NF-kB, so that's where the inflammation comes in, and that leads to oxidized LDLs.

[yuriyfazylov]

That was good. I mean my biochemistry never explained it, so good.

[andrearussell]

Thank you for this clear explanation of A1c. It motivated me to consider again the amount of sugar I consume.

[anthonytamaccio]

Extremely well presented important information.

[wavefuse]

Great and thorough explanation of glycation and HbA1c, which I have many interests and questions about. If possible could I ask this one question ? Once the rbc has been glycated, does it become inactivated and useless for carrying oxygen, and thus someone with high amounts of glycation would see lower oxygen carrying capacity of their blood and maybe even see lower blood oxygen saturation readings? Thanks so much if you have a minute to answer this !

[jerrywalter]

sir grt video but i thought glycosylation mainly occurs at the beta globin chains

[nolwenn]

Thank you for the valuable information, very well explained !

[rani-jmgg]

Sir..
what is the reference u have used for this video?

[r.guerreiro]

If the aldehyde is ethanal, will it activate RAGE as well?