IVF ICSI Procedure - Important things you need to know

ICSI is one of the most important advances in IVF in the last 20 years. There are times when ICSI is mandatory. Learn about ICSI from Dr Randy Morris MD-The BOARD CERTIFIED fertility expert with weekly TTC tips on InfertilityTV

The basic idea behind IVF is that the eggs are removed from the ovaries and fertilized outside of the body in the laboratory. There are two techniques for fertilizing eggs. The older method is called standard insemination. With this technique, a few thousand sperm are placed in a laboratory dish near the egg. The sperm have to penetrate the egg on their own. This method has largely been replaced by ICSI.

#ICSI stands for Intracytoplasmic Sperm Injection. With this technique, a single sperm is injected into a single egg. There are a number of reasons why ICSI is preferred over standard insemination.
First of all, if a man has low sperm counts or poor sperm movement then the chances are higher that fertilization will fail. Sometimes, standard insemination can fail even when the sperm numbers are normal. This is likely due to a specific problem with the sperm not being able to fertilize eggs on their own. Unfortunately, we are not able to predict ahead of time which men have sperm that might fail to fertilize an egg. ICSI bypasses those types of problems, so the chances of an IVF cycle failing because of fertilization failure is a lot lower with ICSI than with standard insemination.

When an egg is removed from the ovary it is surrounded by a dense group of cells called cumulus cells. These cells make it difficult to see the egg under the microscope. This makes it harder to determine if the egg is mature or not. Immature eggs cannot be fertilized. So when there is poor fertilization, it could be in part due to there being many immature eggs rather than a problem with the sperm

When we do ICSI, these cumulus cells are stripped away. This allows us to know with certainty whether an egg is mature and allows more precise evaluation of the egg retrieval.

Finally, ICSI is needed when we are doing genetic testing on embryos. With standard insemination, there may be sperm that didnt fertilize the egg still stuck to the outside of the egg after fertilization. This can cause an incorrect result when trying to do genetic testing of the embryo so ICSI is mandatory when doing genetic testing.

Infertility TV is your weekly source for the best medical information if you have infertility, recurrent miscarriage or are just trying to conceive. (TTC). InfertilityTV covers infertility testing, fertility treatments such as Clomid, Follistim and Crinone and fertility treatments like IUI and IVF (in vitro fertilization).

#IVF #IVFICSI

One of the most popular playlists on InfertilityTV are the TTC tips which are great even you are not struggling with infertility

Dr Morris is a practicing IVF and infertility expert who sees patients at IVF! located in the Naperville Fertility Center.

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[tamarawest]

I have PCOS and I remember how I felt when the doctor told me it would be hard for me to conceive I now have 4 children very successful pregnancies. God blessed me!

[shaizasaeed]

God bless you people for your efforts. Thank you. And please do remember me and my husband. It's getting too emotional to handle.

[namitajoshi]

Hi Doctor Morris, thank you for making so informative videos and helping out the society. I wanted to know your words based on my data below for any suggestions-
Age 38, amh 3+, regular cycle and ovulation, 4 Failed IUI, 2 failed fresh transfer with ICSI,
2 nd ICSI was day5 transfer, took progestrone as suggested in ur videos alternate day injection plus daily thrice vagi.
Hysteroscopy + endoscopy done yesterday-- no scars found, tubes open.
Did blood test for both of us to find any existing genetic issues among us. No issues found. (Embryo genetic testing not available in our part of Germany).
Waiting for results for - Nk killer cells test & uterine plasma test.
We have 3fertilized eggs frozen on day1 left.
Thnku for any suggestion.

[riziadias]

Lovely explanation, clear and straight.

[sindura]

Dr. Randy What is the protocol for Endometriosis via IVF through Donor sperm? And your channel is wonderful✨really great service to humankind.

[CJ-mxvj]

Going for my first retrieval Monday and so scared about fertilization

[HeatSeekingMouse]

Hi Dr Randy. My wife and I have had a son who is now 4. We have been struggling for years to get pregnant. We have both done vitamins, diet and clomid treatment. The Dr says both are conditions are healthy. I have good sperm and she is also tested positive. Therefore we want do ICSI. Can you recommend anyone in Dubai as that is where we live. I wish I could travel to have you perform and assess us.

[lucymendez]

Hi, Dr. Randy Morris! Could you tell us who are the best candidates to be an egg donor?

[ahmedelsayed]

Fantastic 😮❤ i will join the medicine ان شاء الله ❤

[sandhyarani]

After 14 days of my ET. Beta hcg is nagative.what should i do next?my endometrium thin. For thin endometrium any medications are there? Doctor sugged go for surogacy .is it correct.please carify my queriez

[thso]

Doctor i want to ask you what if you ovulate two days after the end of period and you have to take the hormones to do the ICSI for 10 days?

[annakatebertolet]

when did they start using icsi bc im an ivf baby from 2005 so idk which one they used.

[Bluecollarworker]

Great video! Does cannabis usage for males greatly affect success rate of ICSI fertility? Wife does not smoke. I vape lightly nightly before bed to help sleep and back pain.

[someguy]

My IVF clinic did standard insemination of our eggs, then sent out for pgst. Is this wrong? We received a partial deletion of the 8th chromosome. I don’t know how many cells they tested. They retrieved 11 eggs, fertilized 5 and all but 1 arrested and the last one had that aneuploidy result. Sperm count/morphology results were good. Woman is 36 man is 32. IVF doctor is recommending sperm DNA fragmentation test, is that worth doing?

[SajjadAli-yojq]

I have two time pragancy in my tube . Doctor operate me with laser treatment can I conecive again. I have no child please guide me properly

[CJ-mxvj]

My clinic called me today and said my 5 mature eggs were fertilized but developing very slow and it isn’t good And want to
Wait til Tommorow to see if devolpment is any better ? Have you ever heard of this ? I’m so heart broken

[kumarmohan]

Is there any defect for icsi babies.my daughter in law in usa is trying for icsi.after chromosome test they are going to insert embryo.icsi child are normal or any upnorma I am from india.pl reply

[greyjoym]

How long will it take for a sperm to go inside the egg?

[rachealworthen]

Do you have to be on your menstrual cycle to start stimulating the ovaries?

[airalakwatsera]

Hi Dr. I ask if i go ivf better i go icsi procedure than standard?