IVF Expert: Do embryo grades predict IVF success?

Can you pick an embryo that is most likely to produce a live birth simply by looking at it under a microscope? Sounds like an easy question to answer but the reality is far more complex. Dr Randy Morris MD-The BOARD CERTIFIED IVF expert discusses how blastocyst embryos are graded and whether these grades help predict IVF success.

Chapters:
0:00 Introduction
0:19 What are IVF best practices in 2021?
0:50 How are blastocysts graded?
1:50 Problems with grading blastocysts
2:20 Grading may not be predictive for live birth
3:07 Chromosome abnormalities still occur in nice looking embryos
3:50 Grading "normal" embryos may not help
4:05 Do time lapse incubators help predict the best embryo?
5:00 Can artificial intelligence predict the best embryo?


Infertility TV is your weekly source for the best medical information if you have infertility, recurrent miscarriage or are just trying to conceive. (TTC). InfertilityTV covers infertility testing, fertility treatments such as Clomid, Follistim and Crinone and fertility treatments like IUI and IVF (in vitro fertilization)

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Dr Morris is a practicing IVF and infertility expert who sees patients at IVF! located in the Naperville Fertility Center.

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[TheIVFChapters]

Thank you for this interesting video! My understanding is that different clinics (and countries) all use a different grading system. My embryos were all C grade but I'm finally pregnant with my daughter! Don't lose faith if you have a lower grade embryo!

[wildcat]

I found your videos so informative and comforting during my Ivf journey. I’m now 14 weeks but I still enjoy these updates as it helps me remember my journey. Thank you for this valuable resource. It’s more important to people than you might realize.

[Dreamytresses]

Praying for success! I had my retrieval on Monday with 5 mature and 1 immature. Time lapse incubator! ✔ you answered my next question. Thank you!

[ariaXP]

I am a computer engineer and I took some biomedical engineering classes this year. It’s very interesting to me to see if AI and machine learning will be widely used, to assist the doctors in their decision making. I would love to see it help!

[btv]

I really like this doctor and the information he provides. It's factual and helpful. This channel is great

[clairemetters]

This guy is incredible. I love your videos thank you for your such detailed information it’s realy is helpful and answers so many questions x

[MamaBear_]

Very very interesting topic!! It’s so true that grading is just so subjective!! Also, I had 3 embryos that made it to blastocyst/freeze and they were biopsied before freeze. Guess what? I had a 4AA, 4AA, and a 3AB embryos. The Normal ones?? 1 of the 4AA’s and the 3AB!! One of my 4AA’s had chromosomal abnormalities! I thought for sure the 3AB wouldn’t be “Normal” in its chromosomal structures. Well, I was wrong and just goes to show even the “prettiest embryos” aren’t always the best! I’m currently 13w6d pregnant from my PGS normal 4AA embryo and have my other little one, the 3AB waiting for me for transfer sometime in the future 🥰

[madhurimamukhopadhyay]

Hello Dr, I have underwent 3 IVF cycles. All of them failed. Te last cycle I had 5AA blastocyst transfer, it got implanted, got bhcg result 22.58 on day 14 blood test after transfer but on day 18th the result became negative. I did chromosomal genetic testing and it was a normal blastocyst with no complication. May I know the reason for this failure

[drsonalbenchaudhari]

Such beautiful informative video. Completely Reassuring.
Thank you for sparing time❤

[Dr.NestorCastillo]

I would like to hear your specialized opinion about the use of antidepressants and female fertility. I have read several articles pointing out to effects on the pituitary-hypothalamus axis on females affecting FSH levels, and even on heart malformations in the fetus during pregnancy. Have you ever asses this issue in your clinic or with your patients?
Thanks again for such amazing channel with scientific-based information. Highly appreciated!

[WhitneyMoree]

A result of an abnormal B5BB has +1, +8q, -8q (would you transfer this embryo) my doctor can’t explain what it means. HELP

[amgfcuk]

Just transfered a grade 4AA embryo fingers crossed

[sugansugan]

THANK YOU - Learning about this because my daughters is going thru this all now- very helpful

[TheOrthodontist]

Very informative video. My second IVF just failed. And this second time I had 3 AA blastocysts transferred but still none implanted 😢

[fara]

Great video. So if embryo grades are so subjective, why are there so many different gradings? Why not just have a handful that helps determine whether to freeze or not? Really helpful, easy to digest video. Thank you!

[crystalbee]

Great content, I was discussing this topic with an ivf doctor yesterday.

[cecilappleby]

I had rounds 4 IVF total of 5 transfers. The first 2 were normal per PGT but it didn't result to pregnancy. 3rd and 4th no PGT neither pregnancy but on the 5th a 4BB grade embryo without PGT resulted to pregnancy but miscarried at 8 weeks - blighted ovum.

[fiinashafuda]

I'm live in Namibia and like to try it please where are you?

[p.m]

Doctor, what is the success rate for gred B embryo? I'm 40 this year.

[chaabichama]

I just did a transfer of a 4 days embryo i was so surprised when they called me they told me he is développing quickly and reached the blastocyst already. As far as i know his still a morula .